Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes
K Pekayvaz, C Losert, V Knottenberg, C Gold… - Nature Medicine, 2024 - nature.com
Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality.
Inflammation is considered a key pathogenic driver of these diseases, but the underlying …
Inflammation is considered a key pathogenic driver of these diseases, but the underlying …
Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury
E Cortada, J Yao, Y Xia, F Dündar, P Zumbo… - Communications …, 2024 - nature.com
The immune system coordinates the response to cardiac injury and controls regenerative
and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation …
and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation …
Building a single cell transcriptome-based coordinate system for cell ID with SURE
F Zeng, J Han - bioRxiv, 2024 - biorxiv.org
The surge in single-cell transcriptome data necessitates a unified cell identification system.
We propose a strategy that uses metacells as landmarks, coupled with a data-driven method …
We propose a strategy that uses metacells as landmarks, coupled with a data-driven method …
Multi-Omic Factor Analysis uncovers immunological signatures with pathophysiologic and clinical implications in coronary syndromes
K Pekayvaz, C Losert, V Knottenberg, IV van Blokland… - medRxiv, 2023 - medrxiv.org
Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality.
Inflammation is considered to be a key pathogenic driver, but immune states in humans and …
Inflammation is considered to be a key pathogenic driver, but immune states in humans and …
B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure
Cardiovascular disease remains the leading cause of death worldwide. A primary driver of
cardiovascular mortality is ischemic heart failure, a form of cardiac dysfunction that can …
cardiovascular mortality is ischemic heart failure, a form of cardiac dysfunction that can …
B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure
Cardiovascular disease remains the leading cause of death worldwide. A primary driver of
cardiovascular mortality is ischemic heart failure, a form of cardiac dysfunction that can …
cardiovascular mortality is ischemic heart failure, a form of cardiac dysfunction that can …
Bioinformatics Approach to Identify the Relationship among COVID-19, Acute Myocardial Infarction, and Acute Ischemic Stroke
W Chen, X Ye - Next Research, 2025 - Elsevier
Background Severe COVID-19 has been associated with an increased risk of acute
myocardial infarction (AMI) and acute ischemic stroke (AIS), although the specific …
myocardial infarction (AMI) and acute ischemic stroke (AIS), although the specific …
Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury
A Rubio-Navarro, B Perder, M Qiu, AM Pettinato… - search.proquest.com
The immune system coordinates the response to cardiac injury and controls regenerative
and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation …
and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation …
Research briefing
K Pekayvaz, M Heinig - nature.com
A longitudinal multiomic dataset was assembled to characterize the immune landscape in
myocardial infarction and chronic coronary syndromes. Multiomics factor analysis (MOFA) …
myocardial infarction and chronic coronary syndromes. Multiomics factor analysis (MOFA) …