Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs

TK Kim, L Tirloni, E Bencosme-Cuevas, TH Kim… - BMC genomics, 2021 - Springer
Background Lyme disease (LD) caused by Borrelia burgdorferi is the most prevalent tick-
borne disease. There is evidence that vaccines based on tick proteins that promote tick …

Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice

RM Fereig, Y Kuroda, MA Terkawi, ME Mahmoud… - PLoS …, 2017 - journals.plos.org
To develop a vaccine against Toxoplasma gondii, a vaccine antigen with immune-
stimulating activity is required. In the present study, we investigated the immunogenicity and …

Paracoccin induces M1 polarization of macrophages via interaction with TLR4

MS Freitas, AF Oliveira, TA Da Silva… - Frontiers in …, 2016 - frontiersin.org
The fungal human pathogen Paracoccidioides brasiliensis contains paracoccin (PCN), a
multi-domain protein that has lectin and N-acetyl-glucosaminidase activities, which account …

Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle

P Horcajo, D Xia, N Randle, E Collantes-Fernández… - Journal of …, 2018 - Elsevier
Neospora caninum is one of the main causes of transmissible abortion in cattle. Intraspecific
variations in virulence have been widely shown among N. caninum isolates. However, the …

An Extracellular Redox Signal Triggers Calcium Release and Impacts the Asexual Development of Toxoplasma gondii

E Alves, HJ Benns, L Magnus, C Dominicus… - Frontiers in Cellular …, 2021 - frontiersin.org
The ability of an organism to sense and respond to environmental redox fluctuations relies
on a signaling network that is incompletely understood in apicomplexan parasites such as …

Immunocompetent host develops mild intestinal inflammation in acute infection with Toxoplasma gondii

PS Watanabe, AR Trevizan, SE Silva-Filho, MB Góis… - PLoS …, 2018 - journals.plos.org
Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis, common zoonosis
among vertebrates and high incidence worldwide. During the infection, the parasite needs to …

[PDF][PDF] Inflammatory and immune-mediated cutaneous diseases

JAS Quaresma, MN Sotto… - Mediators of …, 2017 - observatorio.fm.usp.br
Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis, common zoonosis
among vertebrates and high incidence worldwide. During the infection, the parasite needs to …

Case Report: Immune Dysregulation Due to Toxoplasma gondii Reactivation After Allogeneic Hematopoietic Cell Transplant

RB Lindell, MS Wolf, AM Alcamo, MA Silverman… - Frontiers in …, 2021 - frontiersin.org
Disseminated toxoplasmosis is an uncommon but highly lethal cause of hyperferritinemic
sepsis after hematopoietic cell transplantation (HCT). We report two cases of disseminated …

Comparative transcriptome analysis of normal and CD44-deleted mouse brain under chronic infection with Toxoplasma gondii

S Li, B He, C Yang, J Yang, L Wang, X Duan, X Deng… - Acta Tropica, 2020 - Elsevier
Toxoplasma gondii is a globally-distributed intracellular parasitic protozoon with wide host
range. Chronic infection is the most prevalent form of T. gondii infection, which can lead to …

Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii.

ESACA De Paula, HC De Oliveira… - Antimicrobial Agents …, 2019 - europepmc.org
The available antifungal therapeutic arsenal is limited. The search for alternative drugs with
fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a …