The packaging of DNA into chromatin in eukaryotes regulates gene transcription, DNA
replication and DNA repair. ATP-dependent chromatin remodelling enzymes (re) arrange …

Emergence of form and function during embryogenesis arises in large part through cell-type-
and cell-state-specific variation in gene expression patterns, mediated by specialized cis …

Nucleosomes are efficient DNA-packaging units. The fundamental protein unit of the
nucleosome is the histone dimer, a simple α-helical domain possessing a highly basic …

In eukaryotes, DNA is organized together with histones and non-histone proteins into a
highly complex nucleoprotein structure called chromatin, with the nucleosome as its …

Post-translational modifications of the histone tails are correlated with distinct chromatin
states that regulate access to DNA. Recent proteomic analyses have revealed several new …

The histone variants H3. 3 and H2A. Z have recently emerged as two of the most important
features in transcriptional regulation, the molecular mechanism of which still remains poorly …

ATP-dependent chromatin remodellers modulate nucleosome dynamics by mobilizing or
disassembling nucleosomes, as well as altering nucleosome composition. These chromatin …

For a couple of decades the chromatin field has endured undeserved neglect. Indeed, what
could be so exciting about a monotonous repeating structure whose purpose in life was to …

Chromatin-remodeling complexes regulate access to nucleosomal DNA by mobilizing
nucleosomes in an ATP-dependent manner. In this study, we find that chromatin remodeling …

Nucleosomes are stable DNA–histone protein complexes that must be unwrapped and
disassembled for genome expression, replication, and repair. Histone posttranslational …