Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …

Role of the MicroRNAs in the pathogenic mechanism of painful symptoms in long COVID: systematic review

S Reyes-Long, JL Cortés-Altamirano… - International Journal of …, 2023 - mdpi.com
The ongoing pandemic of COVID-19 has caused more than 6.7 million tragic deaths, plus, a
large percentage of people who survived it present a myriad of chronic symptoms that last …

Context-dependent regulation of gene expression by non-canonical small RNAs

K Plawgo, KD Raczynska - Non-coding RNA, 2022 - mdpi.com
In recent functional genomics studies, a large number of non-coding RNAs have been
identified. It has become increasingly apparent that noncoding RNAs are crucial players in a …

Profiling levels of serum microRNAs and soluble ACE2 in COVID-19 patients

NM Elemam, H Hasswan, H Aljaibeji, NS Sharif-Askari… - Life, 2022 - mdpi.com
Background: The main mechanism of viral entry in COVID-19 infection is through the
angiotensin-converting enzyme 2 (ACE2) receptor present in the lungs. Numerous studies …

MicroRNAs as potential tools for predicting cancer patients' susceptibility to SARS-CoV-2 infection and vaccination response

TR Dias, F Dias, AL Teixeira, H Sousa, J Oliveira… - Cells, 2022 - mdpi.com
Coronavirus disease (COVID-19) is an infectious disease that is caused by a highly
contagious and severe acute respiratory syndrome—coronavirus 2 (SARS-CoV-2). This …

Host miRNAs as biomarkers of SARS-CoV-2 infection: a critical review

K Pollet, N Garnier, S Szunerits, A Madder… - Sensors & …, 2023 - pubs.rsc.org
MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression, have
received increasing attention as potential biomarkers of different diseases, including viral …

MicroRNAs in the Regulation of RIG-I-like Receptor Signaling Pathway: Possible Strategy for Viral Infection and Cancer

D Chen, Q Ji, J Liu, F Cheng, J Zheng, Y Ma, Y He… - Biomolecules, 2023 - mdpi.com
The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) play a crucial role as pattern-
recognition receptors within the innate immune system. These receptors, present in various …

Identifying MicroRNA markers that predict COVID-19 severity using machine learning methods

J Ren, W Guo, K Feng, T Huang, Y Cai - Life, 2022 - mdpi.com
Individuals with the SARS-CoV-2 infection may experience a wide range of symptoms, from
being asymptomatic to having a mild fever and cough to a severe respiratory impairment that …

The presence of ACE2 and regulatory miRNAs (miR-200c-3p and miR-421-5p) in the saliva of periodontitis patients post-COVID-19 vaccination

BM Bachtiar, N Haerani, Y Soeroso, N Ismah… - Frontiers in Dental …, 2024 - frontiersin.org
The effectiveness of COVID-19 mRNA vaccines in individuals with periodontitis is crucial.
This study evaluated the efficacy of the BNT162b2 vaccine in individuals with periodontitis …

[HTML][HTML] Expression patterns of lncRNA MALAT-1 in SARS-COV-2 infection and its potential effect on disease severity via miR-200c-3p and SIRT1

O Shaker, M El Amir, Y Abd Elfatah, HM Elwi - Biochemistry and Biophysics …, 2023 - Elsevier
Abstract Downregulating Angiotensin Converting Enzyme2 (ACE2) expression may be a
shared mechanism for RNA viruses. Aim Evaluate the expressions of ACE2 effectors: the …