Bioprinting offers a highly-automated and advanced manufacturing platform that facilitates
the deposition of bio-inks (living cells, biomaterials and growth factors) in a scalable and …

Graft inflammation impairs the induction of solid organ transplant tolerance and enhances
acute and chronic rejection. Elucidating the mechanisms by which inflammation is induced …

The advent of more potent immunosuppressants led to the first successful human upper
extremity transplantation in 1998. At this time,> 100 upper extremity transplants, 30 face …

Abstract Three-dimensional (3D) bioprinting is a revolutionary technology in building living
tissues and organs with precise anatomic control and cellular composition. Despite the great …

Organ preservation has been of major importance ever since transplantation developed into
a global clinical activity. The relatively simple procedures were developed on a basic …

β cell replacement with either pancreas or islet transplantation has progressed immensely
over the last decades with current 1-and 5-year insulin independence rates of approximately …

Extracellular vesicles (EVs) play an important role in cell-to-cell communication by delivering
coding and non-coding RNA species and proteins to target cells. Recently, the therapeutic …

The expansion of cells for regenerative therapy will require the genetic dissection of
complex regulatory mechanisms governing the proliferation of non-transformed human cells …

Background Meeting the metabolic demands of donor livers using normothermic ex vivo
liver perfusion (NEVLP) preservation technology is challenging. The delta opioid agonist [D …

Early allograft dysfunction (EAD) after liver transplantation (LT) is associated with inferior
graft survival. EAD is more prevalent in grafts from donation after circulatory death (DCD) …