[HTML][HTML] Chimeric antigen receptor (CAR) T-cell therapy: harnessing extracellular vesicles for enhanced efficacy

B Spokeviciute, S Kholia, MF Brizzi - Pharmacological Research, 2024 - Elsevier
A cutting-edge approach in cell-based immunotherapy for combating resistant cancer
involves genetically engineered chimeric antigen receptor T (CAR-T) lymphocytes. In recent …

Decoding the impact of ageing and environment stressors on skin cell communication

AVS Faria, SS Andrade - Biogerontology, 2025 - Springer
The integumentary system serves as a crucial protective barrier and is subject to complex
signaling pathways that regulate its physiological functions. As the body's first line of …

Exosome-derived microRNAs: emerging players in vitiligo

W Li, Y Pang, Q He, Z Song, X Xie, J Zeng… - Frontiers in …, 2024 - frontiersin.org
Exosome-derived microRNAs (miRNAs) are biomacromolecules and nanoscale
extracellular vesicles originating from intracellular compartments that are secreted by most …

Keratinocytes–Amplifiers of Immune Responses in Systemic Lupus Erythematosus

B Klein, NTK Nguyen, R Moallemian… - Current Rheumatology …, 2025 - Springer
Recent discoveries in KC dysfunction in lupus skin include aberrant IFN responses to
environmental stress, enhanced cytokine and chemokine secretion and epigenetic changes …

Two Coffee Diterpenes, Kahweol and Cafestol, Inhibit Extracellular Melanogenesis: An In Vitro Pilot Study

S Goenka - Biologics, 2024 - mdpi.com
Hyperpigmentation skin disorders are marked by an abnormal accumulation or export of
melanin pigment synthesized within melanocytes and pose a significant aesthetic concern …

Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins

C Luthold, M Didion, E Benedum, AK Burkhart… - bioRxiv, 2024 - biorxiv.org
Dysfunctions in melanocytes can lead to pigmentation disorders, such as albinism, or
contribute to the development of melanoma, the most aggressive form of skin cancer …

Dispensable role of mitf in melanogenesis of Xenopus tropicalis oocytes

H Yi, J Hang, J Shen, S Yang, H Liu, J Deng, S Han… - 2024 - researchsquare.com
Melanin pigmentation in oocytes is a critical feature for both the aesthetic and
developmental aspects of oocytes, influencing their polarity and overall development …