[HTML][HTML] Technical challenges for FLASH proton therapy

S Jolly, H Owen, M Schippers, C Welsch - Physica Medica, 2020 - Elsevier
There is growing interest in the radiotherapy community in the application of FLASH
radiotherapy, wherein the dose is delivered to the entire treatment volume in less than a …

Technical aspects of proton minibeam radiation therapy: Minibeam generation and delivery

T Schneider - Physica Medica, 2022 - Elsevier
Proton minibeam radiation therapy (pMBRT) is a novel therapeutic strategy that combines
the normal tissue sparing of sub-millimetric, spatially fractionated beams with the improved …

Preclinical challenges in proton minibeam radiotherapy: physics and biomedical aspects

G Datzmann, M Sammer, S Girst, M Mayerhofer… - Frontiers in …, 2020 - frontiersin.org
The concept of spatial fractionation in radiotherapy was developed for better sparing of
normal tissue in the entrance channel of radiation. Spatial fractionation utilizing proton …

Beam commissioning of the 35 MeV section in an intensity modulated proton linear accelerator for proton therapy

L Picardi, A Ampollini, G Bazzano, E Cisbani… - … Review Accelerators and …, 2020 - APS
This paper presents the experimental results on the Terapia Oncologica con Protoni-
Intensity Modulated Proton Linear Accelerator (TOP-IMPLART) beam that is currently …

Magnetically focused 70 MeV proton minibeams for preclinical experiments combining a tandem accelerator and a 3 GHz linear post‐accelerator

M Mayerhofer, G Datzmann, A Degiovanni… - Medical …, 2021 - Wiley Online Library
Purpose Radiotherapy plays an important role for the treatment of tumor diseases in two‐
thirds of all cases, but it is limited by side effects in the surrounding healthy tissue. Proton …

Conceptual design of a novel nozzle combined with a clinical proton linac for magnetically focussed minibeams

T Schneider, A Patriarca, A Degiovanni, M Gallas… - Cancers, 2021 - mdpi.com
Simple Summary Proton minibeam radiation therapy (pMBRT) is a novel therapeutic
strategy that combines the tissue sparing potential of submillimetric, spatially fractionated …

The Next Ion Medical Machine Study at CERN: towards a next generation cancer research and therapy facility with ion beams

M Vretenar, D Tommasini, Y Foka, A Lombardi… - 2021 - cds.cern.ch
Cancer therapy with ions has several advantages over X-ray and proton therapy, but its
diffusion remains limited primarily because of the size and cost of the accelerator. To …

[PDF][PDF] First High Quality Drift Tube Linac Cavity additively Manufactured from Pure Copper

M Mayerhofer, J Mittenender… - … of the 14th …, 2023 - athene-forschung.unibw.de
Recently presented RF cavity prototypes printed entirely from pure copper illustrate the
potential of additive manufacturing (AM), and particularly laser powder bed fusion (L-PBF) …

Design of a novel linear accelerator for carbon ion therapy

V Bencini - 2020 - iris.uniroma1.it
Hadron therapy has been first proposed in 1946 by Robert Wilson as an advanced form of
radiotherapy. Hadrons, such as protons and light ions, release the largest part of their …

Radiobiology of Combining Radiotherapy with Other Cancer Treatment Modalities

V Ahire, N Ahmadi Bidakhvidi, T Boterberg… - Radiobiology …, 2023 - Springer
In this chapter, we address the role of radiation as treatment modality in the context of
oncological treatments given to patients. Physical aspects of the use of ionizing radiation …