Abstract Galectin-9 (Gal-9) is a β-galactoside binding lectin known for its immunomodulatory
role in various microbial infections. Gal-9 is expressed in all organ systems and localized in …

Galectins are among the most widely expressed class of lectins in all organisms. They
typically bind β-galactose-containing glycoconjugates and share primary structural …

Many cytosolic proteins lacking a signal peptide, called leaderless cargoes, are secreted
through unconventional secretion. Vesicle trafficking is a major pathway involved. It is …

Proteins are secreted from eukaryotic cells by several mechanisms besides the well-
characterized classical secretory system. Proteins destined to enter the classical secretory …

Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

Over the past few decades, advances in immunological knowledge have led to the
identification of novel immune checkpoints, reinvigorating cancer immunotherapy …

Extracellular vesicles (EVs) are nano-sized particles that hold tremendous potential in the
clinical space, as their biomolecular profiles hold a key to non-invasive liquid biopsy for …

Background Lyme neuroborreliosis, caused by the bacterium Borrelia burgdorferi affects
both the central and peripheral nervous systems (CNS, PNS). The CNS manifestations …

Galectins are β-galactoside-binding proteins that bind and crosslink molecules via their
sugar moieties, forming signaling and adhesion networks involved in cellular …

Galectins are soluble glycan-binding proteins that interact with a wide range of glycoproteins
and glycolipids and modulate a broad spectrum of physiological and pathological …