Cellular senescence: all roads lead to mitochondria
Senescence is a multi‐functional cell fate, characterized by an irreversible cell‐cycle arrest
and a pro‐inflammatory phenotype, commonly known as the senescence‐associated …
and a pro‐inflammatory phenotype, commonly known as the senescence‐associated …
Small-molecule fluorogenic probes for mitochondrial nanoscale imaging
R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …
COVID-19 in children: initial characterization of the pediatric disease
AT Cruz, SL Zeichner - Pediatrics, 2020 - publications.aap.org
POTENTIAL CONFLICT OF INTEREST: The University of Virginia has filed patent
applications related to new technologies for the rapid production of vaccines, and Dr …
applications related to new technologies for the rapid production of vaccines, and Dr …
Split-TurboID enables contact-dependent proximity labeling in cells
Proximity labeling catalyzed by promiscuous enzymes, such as TurboID, have enabled the
proteomic analysis of subcellular regions difficult or impossible to access by conventional …
proteomic analysis of subcellular regions difficult or impossible to access by conventional …
[HTML][HTML] Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Autophagy has been associated with oncogenesis with one of its emerging key functions
being its contribution to the metabolism of tumors. Therefore, deciphering the mechanisms of …
being its contribution to the metabolism of tumors. Therefore, deciphering the mechanisms of …
Regulation of mitochondrial ATP production: Ca2+ signaling and quality control
Cardiac ATP production primarily depends on oxidative phosphorylation in mitochondria
and is dynamically regulated by Ca 2+ levels in the mitochondrial matrix as well as by …
and is dynamically regulated by Ca 2+ levels in the mitochondrial matrix as well as by …
Contact-ID, a tool for profiling organelle contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation
The mitochondria-associated membrane (MAM) has emerged as a cellular signaling hub
regulating various cellular processes. However, its molecular components remain unclear …
regulating various cellular processes. However, its molecular components remain unclear …
Causal roles of mitochondrial dynamics in longevity and healthy aging
Mitochondria are organized in the cell in the form of a dynamic, interconnected network.
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …
Immune aging–A mechanism in autoimmune disease
Evidence is emerging that the process of immune aging is a mechanism leading to
autoimmunity. Over lifetime, the immune system adapts to profound changes in …
autoimmunity. Over lifetime, the immune system adapts to profound changes in …
[HTML][HTML] ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models
Predisposition to Alzheimer's disease (AD) may arise from lipid metabolism perturbation,
however, the underlying mechanism remains elusive. Here, we identify ATPase family AAA …
however, the underlying mechanism remains elusive. Here, we identify ATPase family AAA …