Bromelain‐based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long‐term outcomes

Y Shoham, K Gasteratos, AJ Singer… - International Wound …, 2023 - Wiley Online Library
Abstract In 2012 the European Medicines Agency approved a pineapple stem‐derived
Bromelain‐based debridement concentrate of proteolytic enzymes (NexoBrid®, MediWound …

Enzymatic debridement: past, present, and future

I De Decker, L De Graeve, H Hoeksema… - Acta Chirurgica …, 2022 - Taylor & Francis
Introduction Early surgical debridement of the deep second and third-degree burns is still
the standard of care (SOC) to prepare the wound bed for skin grafting. However, this …

Enzymatic debridement of deep thermal burns in The Russian Federation: first experience

AA Alekseev, NB Malyutina, AE Bobrovnikov… - Life, 2023 - mdpi.com
Since its approval in Europe a decade ago, NexoBrid® enzymatic debridement of deep
thermal burns has been gaining acceptance as standard practice around the world. The …

[PDF][PDF] 重视精准烧伤医学体系的建设与推广

罗高兴, 孙晓艳, 吴军 - 中华烧伤与创面修复杂志, 2023 - zhsszz.xml-journal.net
近年来, 精准医学有了较大的发展, 但由于观念固化, 方法与工具缺乏等原因,
精准医学在烧伤外科中的进展与应用远远落后于其他学科. 该文从烧伤创面面积与深度的精准 …

Preliminary single-center experience of bromelain-based eschar removal in children with mixed deep dermal and full thickness burns

T Korzeniowski, E Grywalska, J Strużyna… - Journal of Clinical …, 2022 - mdpi.com
Introduction: Early eschar removal is the standard management of burns. The goal is to
remove all of the necrotic tissue and render the wound suitable for healing or skin grafting …

A sequential therapeutic hydrogel with injectability and antibacterial activity for deep burn wounds' cleaning and healing

S Wang, J Li, Z Ma, L Sun, L Hou, Y Huang… - … in Bioengineering and …, 2021 - frontiersin.org
As a severe clinical challenge, escharotomy and infection are always the core concerns of
deep burn injuries. However, a usual dressing without multifunctionality leads to intractable …

Bromelain-based enzymatic burn debridement: Spanish multidisciplinary consensus

J Serracanta, J Baena, JR Martinez-Mendez… - European Journal of …, 2023 - Springer
Background Bromelain-based enzymatic debridement is gaining increased interest from
burn specialists in the last few years. The objective of this manuscript is to update the …

Topical agents and dressings for local burn wound care

M Tenehaus, R Hans-Oliver - … /topical-agents-and-dressings-for-local …, 2018 - uptodate.com
Local treatment of burn wounds includes cleansing and debridement and routine burn
wound dressing changes, typically incorporating topical antimicrobial agents; however …

Quality indicators for hospital burn care: a scoping review

DRR Suzuki, LA Santana, JEHG Ávila… - BMC Health Services …, 2024 - Springer
Background Burn treatments are complex, and for this reason, a specialised
multidisciplinary approach is recommended. Evaluating the quality of care provided to acute …

[HTML][HTML] The Effectiveness of an Alloplastic Epidermal Substitute in the Treatment of Burn Wounds in Children: A Comparative Clinical Study of Skin Substitutes and …

A Barbachowska, T Korzeniowski… - Journal of Clinical …, 2024 - mdpi.com
Background: Children make up a large percentage of those affected by burns worldwide,
with most of them suffering from severe injuries that necessitate skilled medical attention …