Triacylglycerols (TAG) serve as the predominant form of energy storage in mammalian cells,
and TAG synthesis influences conditions such as obesity, fatty liver, and insulin resistance …

Phospholipid biosynthesis is a vital facet of bacterial physiology that begins with the
synthesis of the fatty acids by a soluble type II fatty acid synthase. The bacterial glycerol …

We report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria,
a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) …

Most apicomplexan parasites possess a non-photosynthetic plastid (the apicoplast), which
harbors enzymes for a number of metabolic pathways, including a prokaryotic type II fatty …

Triacylglycerols (TAG) are the major form of energy storage in plants. TAG are primarily
stored in seeds and fruits, but vegetative tissues also possess a high capacity for their …

< 1> Canis familiaris (isozymes A and B [1])[1]< 2> Rattus norvegicus (male rats [48];
Sprague-Dawley rats [40]; ST1A1 [40, 48]; AST IV [48]; aryl sulfotransferase IV [32, 48]; a …

Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the initial and rate-limiting step in
glycerolipid synthesis. Several mammalian GPAT activities have been recognized, including …

Glycerophospholipids and triglycerides are synthesized de novo by cells through an
evolutionary conserved process involving serial acylations of phosphorylated glycerol …

The biosynthesis of phospholipids and glycolipids are critical pathways for virtually all cell
membranes. PatA is an essential membrane associated acyltransferase involved in the …

In yeast, phosphatidic acid, the biosynthetic precursor for all glycerophospholipids and
triacylglycerols, is made de novo by the 1-acyl-sn-glycerol-3-phosphate acyltransferases …