Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens

PA Rochon, M Petrovic, A Cherubini… - The Lancet Healthy …, 2021 - thelancet.com
Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

The patterns and implications of potentially suboptimal medicine regimens among older adults: a narrative review

GB Lee, C Etherton-Beer, SM Hosking… - … advances in drug …, 2022 - journals.sagepub.com
In the context of an ageing population, the burden of disease and medicine use is also
expected to increase. As such, medicine safety and preventing avoidable medicine-related …

Sex differences in multimorbidity and polypharmacy trends: a repeated cross-sectional study of older adults in Ontario, Canada

CJ Maxwell, L Mondor, AJ Pefoyo Koné, DB Hogan… - PloS one, 2021 - journals.plos.org
Background Multimorbidity is increasing among older adults, but the impact of these recent
trends on the extent and complexity of polypharmacy and possible variation by sex remains …

[HTML][HTML] Age and sex in drug development and testing for adults

C Tannenbaum, D Day - Pharmacological research, 2017 - Elsevier
Individualization of drug therapy requires that the right drug be administered at the correct
dose to patients who are likely to achieve the highest benefit and lowest risk. Female sex …

Comparative safety of chronic versus intermittent benzodiazepine prescribing in older adults: A population-based cohort study

SJC Davies, D Rudoler, C de Oliveira… - Journal of …, 2022 - journals.sagepub.com
Background: Benzodiazepine treatment recommendations for older adults differ markedly
between guidelines, especially their advice on the acceptability of long-term use. Aims …

Potentially inappropriate medication use in patients with dementia

K Yoon, JT Kim, WG Kwack, D Kim, KT Lee… - International Journal of …, 2022 - mdpi.com
The objective of this study was to characterize the epidemiology of using potentially
inappropriate medications associated with dementia exacerbation (DPIMs) in elderly …

Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA

M Sheikh-Taha, H Dimassi - BMC Cardiovascular Disorders, 2017 - Springer
Background The use of potentially inappropriate medications (PIMs) may pose more risks
than benefits to patients and is a major factor contributing to the likelihood of serious …

Gender differences in potentially inappropriate medication use among older adults

M Alwhaibi, B Balkhi - Pharmaceuticals, 2023 - mdpi.com
Background: Use of potentially inappropriate medication (PIMs) is a prominent concern that
leads to significant medication-related issues among older adults. Notably, older women …

Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity

F Livio, E Deutschmann, G Moffa… - Journal of …, 2021 - academic.oup.com
Background The extent of inappropriate prescribing observed in geriatric medicine has not
been thoroughly evaluated in people ageing with HIV. We determined the prevalence of and …

Appropriateness and adequacy of antibiotic prescription for upper respiratory tract infections in ambulatory health care centers in Ecuador

X Sánchez Choez, ML Armijos Acurio… - BMC Pharmacology and …, 2018 - Springer
Background Upper respiratory tract infections are the leading cause of misuse of antibiotics,
a problem that leads to unnecessary adverse events and antibiotic resistance. Antibiotic …