Although the development of mitochondrial therapies has largely focused on diseases
caused by mutations in mitochondrial DNA or in nuclear genes encoding mitochondrial …

Obesity is one of the most important public health conditions worldwide. Bariatric surgery for
severe obesity is an effective treatment that results in the improvement and remission of …

Background Bariatric (weight loss) surgery for obesity is considered when other treatments
have failed. The effects of the available bariatric procedures compared with medical …

The development of these updated guidelines was commissioned by the AACE, TOS, and
ASMBS Board of Directors and adheres to the AACE 2010 protocol for standardized …

The metabolic syndrome is a condition characterized by a special constellation of reversible
major risk factors for cardiovascular disease and type 2 diabetes. The main, diagnostic …

Obesity has reached global epidemic proportions in both adults and children and is
associated with numerous comorbidities, including hypertension (HTN), type II diabetes …

The recommendations listed in this document are, whenever possible, evidence based.
Writing group members performed these relevant supplemental literature searches with key …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

The rate of obesity is rising logarithmically, especially in those with severe obesity (body
mass index [BMI] 40 kg/m2). Cardiologists, endocrinologists, internists, family practitioners …

Despite considerable scientific progress on the biological systems that regulate energy
balance, we have made precious little headway in providing new treatments to curb the …