Balanced anesthesia relies on the simultaneous administration of different drugs to attain an
anesthetic state. The classic triad of anesthesia is a combination of a hypnotic, an analgesic …

Objective To assess the efficacy of labetalol versus nitroglycerin for induction of controlled
hypotension during sinus endoscopic surgery. Design A prospective, double-blind and …

Purpose We assessed the evidence for the use of α 2-adrenergic agonists (A2AAs) in
bleeding control and field quality in endoscopic sinus surgery. Methods We systematically …

Since its approval by US Food and Drug Administration in 1999 the clinical use of
dexmedetomidine has been gaining in popularity. The indications and clinical applications …

Purpose Intense bleeding of the surgical field is a potential factor influencing success of
functional endoscopic sinus surgery (FESS). Hypotensive anesthesia with α2 intravenous …

Background: Controlled hypotension has been used to reduce bleeding and the need for
blood transfusions and provide a satisfactory bloodless surgical field. In this double-blind …

Background Dexmedetomidine, an α2 agonist, has well-known anesthetic and analgesic-
sparing effects. We designed this study to evaluate the effect of intraoperative …

Background Bleeding during surgery can lead to serious complications. Methods and drugs
to control bleeding are always important both for the surgeon and anesthesiologist …

Background: Clonidine might be beneficial to the patients undergoing laparoscopic
cholecystectomy. This meta-analysis focused on the influence of clonidine on hemodynamic …

Background: Clonidine and dexmedetomidine are alpha-2 receptor blockers administered
for haemorrhage control during surgery in limited settings. Functional endoscopic sinus …