Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

Epigenetic modifications represent mechanisms by which cells may effectively translate
multiple signaling inputs into phenotypic outputs. Recent research is revealing that redox …

Long non-coding RNAs (lncRNAs) are mRNA-like, non-protein-coding RNAs that are
pervasively transcribed throughout eukaryotic genomes. Rather than silently accumulating …

Long non-coding RNAs (lncRNAs) are a heterogeneous class of RNAs that are generally
defined as non-protein-coding transcripts longer than 200 nucleotides. Recently, an …

Genomic imprinting is an epigenetic process leading to parental-specific expression of one
to two percent of mammalian genes that offers one of the best model systems for a molecular …

The central dogma of molecular biology relegates RNAs to the role of “messengers” of
genetic information, with proteins as the end products that perform key roles as regulators …

Long noncoding RNAs (lncRNAs) have emerged as an important class of molecules that
regulate gene expression at epigenetic, transcriptional, and post-transcriptional levels …

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is
poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes …

X-chromosome inactivation (XCI), the random transcriptional silencing of one X
chromosome in somatic cells of female mammals, is a mechanism that ensures equal …