The impact of chromosomal rearrangements in speciation: from micro-to macroevolution
Chromosomal rearrangements (CRs) have been known since almost the beginning of
genetics. While an important role for CRs in speciation has been suggested, evidence …
genetics. While an important role for CRs in speciation has been suggested, evidence …
A holocentric twist to chromosomal speciation?
Chromosomal rearrangements trigger speciation by acting as barriers to gene flow.
However, the underlying theory was developed with monocentric chromosomes in mind …
However, the underlying theory was developed with monocentric chromosomes in mind …
Modular safe-harbor transgene insertion for targeted single-copy and extrachromosomal array integration in Caenorhabditis elegans
Efficient and reproducible transgenesis facilitates and accelerates research using genetic
model organisms. Here, we describe a mo dular s afe-harbor t ransgene i nsertion (MosTI) …
model organisms. Here, we describe a mo dular s afe-harbor t ransgene i nsertion (MosTI) …
Nematode chromosomes
PM Carlton, RE Davis, S Ahmed - Genetics, 2022 - academic.oup.com
The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …
biology, including genetics, development, cell biology, and genomics. A major factor in the …
Centromeric and pericentric transcription and transcripts: their intricate relationships, regulation, and functions
J Zhu, Q Guo, M Choi, Z Liang, KWY Yuen - Chromosoma, 2023 - Springer
Centromeres are no longer considered to be silent. Both centromeric and pericentric
transcription have been discovered, and their RNA transcripts have been characterized and …
transcription have been discovered, and their RNA transcripts have been characterized and …
High-throughput library transgenesis in Caenorhabditis elegans via Transgenic Arrays Resulting in Diversity of Integrated Sequences (TARDIS)
ZC Stevenson, MJ Moerdyk-Schauwecker, SA Banse… - Elife, 2023 - elifesciences.org
High-throughput transgenesis using synthetic DNA libraries is a powerful method for
systematically exploring genetic function. Diverse synthesized libraries have been used for …
systematically exploring genetic function. Diverse synthesized libraries have been used for …
Argonaute protein CSR-1 restricts localization of holocentromere protein HCP-3, the C. elegans CENP-A homolog
CYY Wong, HN Tsui, Y Wang… - Journal of Cell …, 2024 - journals.biologists.com
Chromosome segregation errors caused by centromere malfunction can lead to
chromosome instability and aneuploidy. In Caenorhabditis elegans, the Argonaute protein …
chromosome instability and aneuploidy. In Caenorhabditis elegans, the Argonaute protein …
[HTML][HTML] The roles of transcription, chromatin organisation and chromosomal processes in holocentromere establishment and maintenance
Y Wang, L Wu, KWY Yuen - Seminars in Cell & Developmental Biology, 2022 - Elsevier
The centromere is a unique functional region on each eukaryotic chromosome where the
kinetochore assembles and orchestrates microtubule attachment and chromosome …
kinetochore assembles and orchestrates microtubule attachment and chromosome …
[PDF][PDF] Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species
Centromeric histones (CenH3s) are essential for chromosome inheritance during cell
division in most eukaryotes. CenH3 genes have rapidly evolved and undergone repeated …
division in most eukaryotes. CenH3 genes have rapidly evolved and undergone repeated …
CSR-1 RNA interference pathway restricts holocentromere protein CENP-A/HCP-3 localization in Caenorhabditis elegans
CY Yu Wong, KW Yee Yuen - bioRxiv, 2022 - biorxiv.org
CSR-1 is an argonaute of a RNA interference pathway that is important for chromosome
segregation in C. elegans. Live-cell imaging revealed that CSR-1 depletion slows down …
segregation in C. elegans. Live-cell imaging revealed that CSR-1 depletion slows down …