Polymer translocation and nanopore sequencing: a review of advances and challenges

SL Singh, K Chauhan, AS Bharadwaj… - International Journal of …, 2023 - mdpi.com
Various biological processes involve the translocation of macromolecules across
nanopores; these pores are basically protein channels embedded in membranes …

Connexin-containing vesicles for drug delivery

MS Hanafy, Z Cui - The AAPS Journal, 2024 - Springer
Connexin is a transmembrane protein present on the cell membrane of most cell types.
Connexins assemble into a hexameric hemichannel known as connexon that pairs with …

Ion transport and current rectification in a charged conical nanopore filled with viscoelastic fluids

M Trivedi, N Nirmalkar - Scientific Reports, 2022 - nature.com
The ionic current rectification (ICR) is a non-linear current-voltage response upon switching
the polarity of the potential across nanopore which is similar to the I–V response in the …

Gap junction-mediated delivery of polymeric macromolecules

AN Trementozzi, C Zhao, H Smyth, Z Cui… - ACS biomaterials …, 2022 - ACS Publications
Cellular delivery of therapeutic macromolecules such as proteins, peptides, and nucleic
acids remains limited due to inefficient transport across the cellular plasma membrane. Gap …

Polymer translocation driven by longitudinal and transversal time-dependent end-pulling forces

A Sainz-Agost, F Falo, A Fiasconaro - Physical Review E, 2023 - APS
In this article, we simulate the translocation of a semiflexible homopolymer through an
extended pore, driven by both a constant and a time-dependent end-pulled force, employing …

A Monte Carlo study on a 3-dimensional comb polymer translocation through a nanopore driven by an electric field

TB Bruh, YB Tatek - … and Simulation in Materials Science and …, 2024 - iopscience.iop.org
A lattice Monte Carlo simulation study of the translocation of comb polymers through a
nanopore subjected to an electric field is presented. The translocation dynamics was …

Simulation study of chain-like body translocation through conical pores in thick membranes

Z Domański, AZ Grzybowski - Membranes, 2022 - mdpi.com
Artificial membranes with conical pores and controllable thickness reveal ionic-transport
capabilities that are superior compared with those offered by cylindrical pores. By simulating …

Nanoparticle-assisted polymer translocation through a nanopore

MN Hamidabad, S Asgari, RH Abdolvahab - Polymer, 2020 - Elsevier
The effect of interaction between immobile nanoparticle and polymer on the translocation
process was investigated using a three dimensional Langevin molecular dynamics. Several …

Constraints on Knot Insertion, Not Internal Jamming, Control Polycatenane Translocation Dynamics through Crystalline Pores

Z Wang, RM Ziolek, M Tsige - Macromolecules, 2023 - ACS Publications
The translocation of polymers through pores and channels is an archetypal process in
biology and is widely studied and exploited for applications in bio-and nanotechnology. In …

Time Estimation of Polymer Translocation through Nano-Membrane

MA Paun, VA Paun, VP Paun - Polymers, 2022 - mdpi.com
In this paper, the charged polymer escapement phenomenon, via a little hole of nano-metric
dimensions arranged in a constitutive biological membrane, is studied. We will present the …