Introduction: Persistent infections caused by the superbug Pseudomonas aeruginosa and its
resistance to multiple antimicrobial agents are huge threats to patients with cystic fibrosis as …

The fifth edition of Pathogenesis of Bacterial Infections in Animals tries to capture the many
fascinating and rapid developments in our understanding of how major bacterial pathogens …

σ54 factor (RpoN), a type of transcriptional regulatory factor, is widely found in pathogenic
bacteria. It binds to core RNA polymerase (RNAP) and regulates the transcription of many …

The present work examines the evolutionary trajectories of replicate Pseudomonas
aeruginosa cultures in presence of the ribosome-targeting antibiotics tobramycin and …

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen of humans,
particularly those with cystic fibrosis. As a global regulator, RpoN controls a group of …

Pseudomonas aeruginosa is a major cause of nosocomial infections and the leading cause
of chronic lung infections in cystic fibrosis and chronic obstructive pulmonary disease …

The human pathogen Pseudomonas aeruginosa produces a variety of virulence factors
including pyoverdine, a nonribosomally produced peptide siderophore. The maturation …

Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that infects
immunocompromised and cystic fibrosis patients. Treatment is difficult due to antibiotic …

Pseudomonas aeruginosa has developed diverse strategies to respond and adapt to
antibiotic stress. Among the factors that modulate survival in the presence of antibiotics …

The basis of the bactericidal action of antibiotics and the mechanisms of antibiotic tolerance
are largely unknown. To elucidate one of the mechanisms of antibiotic tolerance, the present …