Synthesis of bacterial polysaccharides via the Wzx/Wzy-dependent pathway

ST Islam, JS Lam - Canadian journal of microbiology, 2014 - cdnsciencepub.com
The surfaces of bacteria mediate a multitude of functions in the environment and in an
infected host, including adhesion to both biotic and abiotic substrata, motility, immune …

Genetic and Functional Diversity of Pseudomonas aeruginosa Lipopolysaccharide

JS Lam, VL Taylor, ST Islam, Y Hao… - Frontiers in …, 2011 - frontiersin.org
Lipopolysccharide (LPS) is an integral component of the Pseudomonas aeruginosa cell
envelope, occupying the outer leaflet of the outer membrane in this Gram-negative …

Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post‐transcriptionally regulated

L Ma, J Wang, S Wang, EM Anderson… - Environmental …, 2012 - Wiley Online Library
Exopolysaccharide is a critical biofilm matrix component, yet little is known about how the
synthesis of multiple exopolysaccharides is regulated. Pseudomonas aeruginosa can …

Synthesis of rhizobial exopolysaccharides and their importance for symbiosis with legume plants

M Marczak, A Mazur, P Koper, K Żebracki, A Skorupska - Genes, 2017 - mdpi.com
Rhizobia dwell and multiply in the soil and represent a unique group of bacteria able to
enter into a symbiotic interaction with plants from the Fabaceae family and fix atmospheric …

Wzx flippase‐mediated membrane translocation of sugar polymer precursors in bacteria

ST Islam, JS Lam - Environmental microbiology, 2013 - Wiley Online Library
Bacterial cell surface polysaccharides confer resistance to external stress and promote
survival in biotic and abiotic environments. Glycan assembly often occurs at the periplasmic …

Repeat-unit elongations to produce bacterial complex long polysaccharide chains, an O-antigen perspective

Y Hong, D Hu, AD Verderosa, J Qin, M Totsika… - EcoSal …, 2023 - Am Soc Microbiol
The O-antigen, a long polysaccharide that constitutes the distal part of the outer membrane-
anchored lipopolysaccharide, is one of the critical components in the protective outer …

The mysterious nature of bacterial surface (gliding) motility: a focal adhesion-based mechanism in Myxococcus xanthus

ST Islam, T Mignot - Seminars in cell & developmental biology, 2015 - Elsevier
Motility of bacterial cells promotes a range of important physiological phenomena such as
nutrient detection, harm avoidance, biofilm formation, and pathogenesis. While much …

Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion

ST Islam, I Vergara Alvarez, F Saïdi, A Guiseppi… - PLoS …, 2020 - journals.plos.org
The development of multicellularity is a key evolutionary transition allowing for differentiation
of physiological functions across a cell population that confers survival benefits; among …

Defining function of lipopolysaccharide O-antigen ligase WaaL using chemoenzymatically synthesized substrates

W Han, B Wu, L Li, G Zhao, R Woodward… - Journal of Biological …, 2012 - ASBMB
The WaaL-mediated ligation of O-antigen onto the core region of the lipid A-core block is an
important step in the lipopolysaccharide (LPS) biosynthetic pathway. Although the LPS …

Challenges and perspectives in combinatorial assembly of novel exopolysaccharide biosynthesis pathways

A Becker - Frontiers in Microbiology, 2015 - frontiersin.org
Because of their rheological properties various microbial polysaccharides are applied as
thickeners and viscosifiers both in food and non-food industries. A broad variety of …