Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomized trials

F Costa, C Montalto, M Branca, SJ Hong… - European Heart …, 2023 - academic.oup.com
Aims The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary
intervention (PCI) in patients at high bleeding risk (HBR) is still debated. The current study …

Current concepts and novel targets for antiplatelet therapy

M Gawaz, T Geisler, O Borst - Nature Reviews Cardiology, 2023 - nature.com
Platelets have a crucial role in haemostasis and atherothrombosis. Pharmacological control
of platelet hyper-reactivity has become a cornerstone in the prevention of thrombo …

P2Y12 Inhibitor Monotherapy or Dual Antiplatelet Therapy After Complex Percutaneous Coronary Interventions

F Gragnano, R Mehran, M Branca, A Franzone… - Journal of the American …, 2023 - jacc.org
Background It remains unclear whether P2Y12 inhibitor monotherapy preserves ischemic
protection while limiting bleeding risk compared with dual antiplatelet therapy (DAPT) after …

Antithrombotic treatment strategies in patients with established coronary atherosclerotic disease

M Valgimigli, V Aboyans, D Angiolillo… - European Heart …, 2023 - academic.oup.com
Multiple guidelines and consensus papers have addressed the role of antithrombotic
strategies in patients with established coronary artery disease (CAD). Since evidence and …

Demystifying the contemporary role of 12-month dual antiplatelet therapy after acute coronary syndrome

M Valgimigli, A Landi, DJ Angiolillo, U Baber, DL Bhatt… - Circulation, 2024 - ahajournals.org
For almost two decades, 12-month dual antiplatelet therapy (DAPT) in acute coronary
syndrome (ACS) has been the only class I recommendation on DAPT in American and …

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Ticagrelor or clopidogrel monotherapy vs dual antiplatelet therapy after percutaneous coronary intervention: a systematic review and patient-level meta-analysis

M Valgimigli, F Gragnano, M Branca… - JAMA …, 2024 - jamanetwork.com
Importance Among patients undergoing percutaneous coronary intervention (PCI), it
remains unclear whether the treatment efficacy of P2Y 12 inhibitor monotherapy after a short …

Abbreviated antiplatelet therapy after coronary stenting in patients with myocardial infarction at high bleeding risk

PC Smits, E Frigoli, P Vranckx, Y Ozaki… - Journal of the American …, 2022 - jacc.org
Background The optimal duration of antiplatelet therapy (APT) after coronary stenting in
patients at high bleeding risk (HBR) presenting with an acute coronary syndrome remains …

Short dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk patients: Systematic review and meta-analysis

KR Bainey, G Marquis-Gravel, BJ MacDonald… - Plos one, 2023 - journals.plos.org
Introduction Dual antiplatelet therapy (DAPT) following percutaneous coronary intervention
(PCI) reduces major adverse cardiovascular events (MACE) and stent thrombosis. However …

[HTML][HTML] Safety and efficacy of shortened dual antiplatelet therapy after complex percutaneous coronary intervention: A systematic review and meta-analysis

A Apostolos, D Chlorogiannis, G Vasilagkos… - Hellenic Journal of …, 2023 - Elsevier
Background Optimal duration of dual antiplatelet therapy (DAPT) in patients undergoing
complex percutaneous coronary intervention (PCI) remains under investigation. Our aim is …