Physical exercise represents a major challenge to whole-body homeostasis, provoking
acute and adaptative responses at the cellular and systemic levels. Different sources of …

It is well established that regimented resistance training can promote increases in muscle
hypertrophy. The prevailing body of research indicates that mechanical stress is the primary …

Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and
contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide …

Generation of reactive oxygen species (ROS) is a ubiquitous phenomenon in eukaryotic
cells′ life. Up to the 1990s of the past century, ROS have been solely considered as toxic …

This review offers an overview of the influence of reactive species produced during exercise
and their effect on exercise adaptation. Reactive species and free radicals are unstable …

Schoenfeld, BJ. Does exercise-induced muscle damage play a role in skeletal muscle
hypertrophy? J Strength Cond Res 26 (5): 1441–1453, 2012—Exercise-induced muscle …

Science and Development of Muscle Hypertrophy, Second Edition, is the most
comprehensive resource on muscle hypertrophy in the world. Written by Brad Schoenfeld …

Objectives The myoblast cell line, C2C12, has been utilised extensively in vitro as an
examination model in understanding metabolic disease progression. Although it is …

Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

Metabolic stress is a physiological process that occurs during exercise in response to low
energy that leads to metabolite accumulation [lactate, phosphate inorganic (Pi) and ions of …