Six CO 2 fixation pathways are known to operate in photoautotrophic and chemoautotrophic
microorganisms. Here, we describe chemolithoautotrophic growth of the sulphate-reducing …

We describe the anaerobic conversion of inositol stereoisomers to propionate and acetate
by the abundant intestinal genus Anaerostipes. A inositol pathway was elucidated by …

Nanoscale or single-cell technologies are critical for biomedical applications. However,
current mass spectrometry (MS)-based proteomic approaches require samples comprising a …

Spaceflight is known to impose changes on human physiology with unknown molecular
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical …

This study shows that the supramolecular arrangement of proteins in nanoparticle structures
predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We …

Akkermansia muciniphila is a well-studied anaerobic bacterium specialized in mucus
degradation and associated with human health. Because of the structural resemblance of …

Numerous software tools exist for data-independent acquisition (DIA) analysis of clinical
samples, necessitating their comprehensive benchmarking. We present a benchmark …

Robust, efficient, and reproducible protein extraction and sample processing is a key step for
bottom-up proteomics analyses. While many sample preparation protocols for mass …

Abstract MALDI-TOF MS technique is commonly used in system biology and clinical studies
to search for new potential markers associated with pathological conditions. Despite …

The increasing number of biomedical and translational applications in mass spectrometry-
based proteomics poses new analytical challenges and raises the need for automated …