Hemophagocytic lymphohistiocytosis: review of etiologies and management

MR George - Journal of blood medicine, 2014 - Taylor & Francis
Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening
conditions featuring ineffective immunity characterized by an uncontrolled …

Infections associated with haemophagocytic syndrome

NG Rouphael, NJ Talati, C Vaughan… - The Lancet infectious …, 2007 - thelancet.com
Haemophagocytic syndrome or haemophagocytic lymphohistiocytosis is a rare disease that
is often fatal despite treatment. Haemophagocytic syndrome is caused by a dysregulation in …

A question of self‐preservation: immunopathology in influenza virus infection

NL La Gruta, K Kedzierska, J Stambas… - Immunology and cell …, 2007 - Wiley Online Library
Influenza A viruses that circulate normally in the human population cause a debilitating,
though generally transient, illness that is sometimes fatal, particularly in the elderly. Severe …

Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage …

L Castillo, J Carcillo - Pediatric Critical Care Medicine, 2009 - journals.lww.com
In an effort to attain earlier diagnoses in children with hemophagocytic lymphohistiocytosis
(HLH), the International Histiocyte Society has now broadened their diagnostic criteria to no …

Viral infections associated with haemophagocytic syndrome

NR Maakaroun, A Moanna, JT Jacob… - Reviews in medical …, 2010 - Wiley Online Library
Haemophagocytic syndrome (HPS) or haemophagocytic lymphohistiocytosis (HLH) is a rare
disease caused by a dysfunction of cytotoxic T cells and NK cells. This T cell/NK cell …

Potential specific therapies in COVID-19

MH Gul, ZM Htun, N Shaukat… - … in respiratory disease, 2020 - journals.sagepub.com
COVID-19 has grown into a global pandemic that has strained healthcare throughout the
world. There is a sense of urgency in finding a cure for this deadly virus. In this study, we …

Presentations and outcomes of familial hemophagocytic lymphohistiocytosis in the pediatric intensive care units (PICUs)

F Alsohime, MH Temsah, RM Alotaibi… - Frontiers in …, 2023 - frontiersin.org
Objectives We aimed to describe Familial Hemophagocytic Lymphohistiocytosis (F-HLH)
patients' clinical features, intensive care courses, and outcomes. Methods Multi-center …

Debate around infection-dependent hemophagocytic syndrome in paediatrics

V Ansuini, D Rigante, S Esposito - BMC Infectious Diseases, 2013 - Springer
Background Hemophagocytic syndrome (HPS) is clinically defined as a combination of
fever, liver dysfunction, coagulation abnormalities, pancytopenia, progressive macrophage …

[HTML][HTML] Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failure

VL Capelozzi, ER Parra, M Ximenes, RH Bammann… - Clinics, 2010 - Elsevier
BACKGROUND: Cases of H1N1 and other pulmonary infections evolve to acute respiratory
failure and death when co-infections or lung injury predominate over the immune response …

Macrophage activation syndrome

EM Eloseily, RQ Cron - The microbiome in rheumatic diseases and …, 2018 - Springer
Hemophagocytic lymphohistiocytosis (HLH), or termed macrophage activation syndrome
(MAS) when associated with rheumatic disorders, is a frequently fatal complication of …