During erythropoiesis, there is an enormous demand for the synthesis of the essential
cofactor of hemoglobin, heme. Heme is synthesized de novo via an eight enzyme-catalyzed …

Many annelids can regenerate missing body parts or reproduce asexually, generating all
cell types in adult stages. However, the putative adult stem cell populations involved in these …

Our globin census update allows us to refine our vision of globin origin, evolution, and
structure to function relationship in the context of the currently accepted tree of life. The …

The capacity to regenerate lost tissues varies significantly among animals. Some phyla,
such as the annelids, display substantial regenerating abilities, although little is known …

Platynereis dumerilii, a marine annelid, is a model animal that has gained popularity in
various fields such as developmental biology, biological rhythms, nervous system …

Regeneration of missing body parts can be observed in diverse animal phyla, but it remains
unclear to which extent these capacities rely on shared or divergent principles. Research …

Electron microscopy (EM) provides a uniquely detailed view of cellular morphology,
including organelles and fine subcellular ultrastructure. While the acquisition and (semi-) …

Chemosynthesis-based ecosystems such as hydrothermal vents and hydrocarbon seeps
harbour various endemic species, each uniquely adapted to the extreme conditions. While …

Extinction selectivity determines the direction of macroevolution, especially during mass
extinction; however, its driving mechanisms remain poorly understood. By investigating the …

The types of genomic change needed for environmental adaptation are of great interest.
Annelid worms are a large phylum found in a rich diversity of habitats, giving opportunities to …