The glomerular filtration barrier: a structural target for novel kidney therapies

IS Daehn, JS Duffield - Nature Reviews Drug Discovery, 2021 - nature.com
Loss of normal kidney function affects more than 10% of the population and contributes to
morbidity and mortality. Kidney diseases are currently treated with immunosuppressive …

Nitric oxide signalling in cardiovascular health and disease

C Farah, LYM Michel, JL Balligand - Nature Reviews Cardiology, 2018 - nature.com
Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

[HTML][HTML] Endothelial nitric oxide synthase (eNOS) and the cardiovascular system: in physiology and in disease states

N Tran, T Garcia, M Aniqa, S Ali, A Ally… - American journal of …, 2022 - ncbi.nlm.nih.gov
Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a
healthy cardiovascular system. The importance of eNOS can be emphasized from the …

Obesity and preeclampsia: common pathophysiological mechanisms

P Lopez-Jaramillo, J Barajas… - Frontiers in …, 2018 - frontiersin.org
Preeclampsia is a disorder specific of the human being that appears after 20 weeks of
pregnancy, characterized by new onset of hypertension and proteinuria. Abnormal …

[图书][B] Генетический паспорт–основа индивидуальной и предиктивной медицины

В Баранов - 2022 - books.google.com
В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

Preeclampsia: long-term consequences for vascular health

LM Amaral, MW Cunningham Jr… - Vascular health and …, 2015 - Taylor & Francis
Preeclampsia (PE) is a pregnancy-specific syndrome and one of the leading causes of
preterm birth, neonatal and maternal morbidity and mortality. This disease is characterized …

Preeclampsia 2012

E Eiland, C Nzerue, M Faulkner - Journal of pregnancy, 2012 - Wiley Online Library
Preeclampsia is a common complication of pregnancy associated with high maternal
morbidity and mortality and intrauterine fetal growth restriction. There is extensive evidence …

[HTML][HTML] Endothelial dysfunction; an important mediator in the Pathophysiology of Hypertension during Preeclampsia

B LaMarca - Minerva ginecologica, 2012 - ncbi.nlm.nih.gov
Preeclampsia is defined as new onset hypertension with proteinuria during pregnancy. It
affects approximately 5% of pregnancies in the US with a subset of those progressing into …

Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms

GH Oliveira-Paula, R Lacchini, JE Tanus-Santos - Gene, 2016 - Elsevier
Nitric oxide (NO) is an important vasodilator with a well-established role in cardiovascular
homeostasis. While mediator is synthesized from L-arginine by neuronal, endothelial, and …

Endothelial dysfunction: a link among preeclampsia, recurrent pregnancy loss, and future cardiovascular events?

AM Germain, MC Romanik, I Guerra, S Solari… - …, 2007 - Am Heart Assoc
We tested the hypothesis that endothelial dysfunction could cause placentation-related
defects, persist after the complicated pregnancy, and probably cause cardiovascular …