Cardiac growth and remodeling (G&R) refers to structural changes in myocardial tissue in
response to chronic alterations in loading conditions. One such condition is pressure …

Background Sustained pressure overload leads to changes in cardiac metabolism, function,
and structure. Both time course and causal relationships between these changes are not …

Single or combinatorial administration of β-blockers is a mainstay treatment strategy for
conditions caused by sympathetic overactivity. Conventional wisdom suggests that the main …

The treatment of hypertensive patients with losartan is very common. Despite the reduction
in blood pressure, its effects on cardiac contractility and sympathetic autonomic drive are still …

Ethnopharmacological relevance Salvianolic acid D (Sal D) is a natural substance extracted
from Radix Salviae that performs a cardiovascular benefit. However, the protective …

Background: Minors are considered the main consumer group of energy drinks (EDs). The
aim of this study was to investigate the acute effects of ED consumption on left ventricular …

Background: Left ventricular (LV) global longitudinal strain (GLS) has been proposed as an
early imaging biomarker of cardiac mechanical dysfunction. Objective: To assess the impact …

Cardiovascular disease is the most prevalent age-related illness worldwide, causing
approximately 15 million deaths every year. Hypertension is central in determining …

Heart failure (HF) is one of the leading causes of death worldwide. HF is associated with
substantial microstructural remodeling, which is linked to changes in left ventricular …

Cardiomyocyte growth can occur in both physiological (exercised-induced) and pathological
(eg, volume overload and pressure overload) conditions leading to left ventricular (LV) …