Macrophages are present in nearly all tissues and are critical for development, homeostasis,
and regeneration. Resident tissue macrophages of bone, termed osteal macrophages, are …

Bone is in a constant state of remodeling, a process which was once attributed solely to
osteoblasts and osteoclasts. Decades of research has identified many other populations of …

Cellular subpopulations in the bone marrow play distinct and unexplored functions in
skeletal homeostasis. This study delineated a unique role of osteal macrophages in bone …

Tumor cells secrete factors that modulate macrophage activation and polarization into M2
type tumor-associated macrophages, which promote tumor growth, progression, and …

Imidacloprid (IMI) is one of the most frequently used neonicotinoid insecticide, and its
potential toxicity and environmental hazards have gradually attracted people's attention …

Periodontitis is a periodontal inflammatory condition that results from disrupted periodontal
host–microbe homeostasis, manifested by the destruction of tooth-supporting structures …

Purpose Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading
cause of visual disability and blindness in diabetic patients. Chronic hyperglycemia leads to …

Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are
characterized by ineffective hematopoiesis and an increased risk of transformation into …

Teriparatide is a bone anabolic treatment for osteoporosis, modeled in animals by
intermittent PTH (iPTH) administration, but the cellular and molecular mechanisms of action …

Diverse pathogens are detected in Alzheimer's disease (AD) brains. A bioinformatics survey
showed that AD genome-wide association study (GWAS) genes (localized in bone marrow …