Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy

W Cao, M Jin, K Yang, B Chen, M Xiong, X Li… - Journal of …, 2021 - Springer
Chemodynamic therapy (CDT) catalyzed by transition metal and starvation therapy
catalyzed by intracellular metabolite oxidases are both classic tumor treatments based on …

Physiology of the prion protein

R Linden, VR Martins, MAM Prado… - Physiological …, 2008 - journals.physiology.org
Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …

Metals and Alzheimer's disease

PA Adlard, AI Bush - Journal of Alzheimer's disease, 2006 - content.iospress.com
There is increasing evidence to support a role for both the amyloid β-protein precursor
(AβPP) and its proteolytic fragment, amyloid β (Aβ), in metal ion homeostasis. Furthermore …

Copper: an intracellular achilles' heel allowing the targeting of epigenetics, kinase pathways, and cell metabolism in cancer therapeutics

F Michniewicz, F Saletta, JRC Rouaen… - …, 2021 - Wiley Online Library
Copper is an essential transition metal frequently increased in cancer known to strongly
influence essential cellular processes. Targeted therapy protocols utilizing both novel and …

Cell death mediated by nanotechnology via the cuproptosis pathway: a novel horizon for cancer therapy

C Wei, Q Fu - View, 2023 - Wiley Online Library
Cuproptosis, the current form of regulated cell death characterized by copper overload,
oligomerization of lipoacylated proteins, and loss of Fe–S cluster proteins, has been …

A microdots array-based fluoremetric assay with superwettability profile for simultaneous and separate analysis of iron and copper in red wine

C Xu, Q Liu, S Chu, P Li, F Wang, Y Si, G Mao… - Analytica Chimica …, 2023 - Elsevier
A microdots array-based fluoremetric method with superwettability profile has been
developed for the simultaneous and separate detection of Fe 3+ and Cu 2+ ions in red wine …

Copper & biological health

S Krupanidhi, A Sreekumar… - Indian Journal of Medical …, 2008 - journals.lww.com
Cu being a transition metal is ubiquitously engaged in biological systems to derive electrons
through its participation in several enzymatic reactions. Upon bestowing the significance of …

Characterization of biometal profiles in neurological disorders

S Pfaender, AM Grabrucker - Metallomics, 2014 - academic.oup.com
Many neurodegenerative and neuropsychiatric disorders have been reported to coincide
with the dysregulation of metal ions in the body and central nervous system. However, in …

The relevance of metals in the pathophysiology of neurodegeneration, pathological considerations

KA Jellinger - International review of neurobiology, 2013 - Elsevier
Neurodegenerative disorders are featured by a variety of pathological conditions that share
similar critical processes, such as oxidative stress, free radical activity, proteinaceous …

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

JA Ríos, P Cisternas, M Arrese, S Barja… - Progress in …, 2014 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, affecting more than 36
million people worldwide. AD is characterized by a progressive loss of cognitive functions …