Osteopontin (OPN) is an extracellular matrix protein that is overexpressed in various cancers
and promotes oncogenic features including cell proliferation, survival, migration, and …

Human osteopontin (OPN) is a glycosylated phosphoprotein which is expressed in a variety
of tissues in the body. In recent years, accumulating evidence has indicated that the aberrant …

In this study, we performed a comprehensively analysis of gene expression and DNA
methylation data to establish diagnostic, prognostic, and recurrence models for …

Objective Tumor metastasis is still a great challenge for the prognosis of colorectal cancer
(CRC). Although secreted phosphoprotein 1 (SPP1) over-expression is confirmed to …

Osteopontin (OPN) is a matricellular protein overexpressed in cancer cells and modulates
tumorigenesis and metastasis, including in thyroid cancer (TC). The contribution of each …

Thyroid cancer is the most common tumor arising from the endocrine system and generally
presents good prognosis. However, its aggressive subtypes are related to therapeutic …

Osteopontin (OPN) is critical for ischemia-induced neovascularization. Unlike rodents,
humans express three OPN isoforms (a, b, and c); however, the roles of these isoforms in …

Background Microcalcification is a very important diagnostic information in breast cancer.
The purpose of this study was to determine the relationship of clinicopathological features …

Osteopontin (OPN) is a protein expressed in several tissues, including bone marrow, in
which it performs distinct roles, such as modulating hematopoietic stem cell niche and bone …

Osteopontin (OPN) spliced variants (OPN-SV: OPNa, OPNb, and OPNc) are aberrantly
expressed in tumors and frequently associated with cancer progression. This holds true for …