Predisposing and precipitating factors associated with delirium: a systematic review

CH Ormseth, SC LaHue, MA Oldham… - JAMA network …, 2023 - jamanetwork.com
Importance Despite discrete etiologies leading to delirium, it is treated as a common end
point in hospital and in clinical trials, and delirium research may be hampered by the attempt …

Neuropathogenesis of delirium: review of current etiologic theories and common pathways

JR Maldonado - The American Journal of Geriatric Psychiatry, 2013 - Elsevier
Delirium is a neurobehavioral syndrome caused by dysregulation of neuronal activity
secondary to systemic disturbances. Over time, a number of theories have been proposed in …

Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network …

AB Lopez‐Rodriguez, E Hennessy… - Alzheimer's & …, 2021 - Wiley Online Library
Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary
inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular …

The risk factors for postoperative delirium in adult patients after hip fracture surgery: a systematic review and meta‐analysis

J Wu, Y Yin, M Jin, B Li - International journal of geriatric …, 2021 - Wiley Online Library
Objectives Postoperative delirium (POD) is the most common complication in patients after
hip fracture surgery, and the incidence of POD is associated with mortality and disability in …

Pre-operative indicators for mortality following hip fracture surgery: a systematic review and meta-analysis

T Smith, K Pelpola, M Ball, A Ong, PK Myint - Age and ageing, 2014 - academic.oup.com
Objective: hip fracture is a common and serious condition associated with high mortality.
This study aimed to identify pre-operative characteristics which are associated with an …

Sleep, pain, and cognition: modifiable targets for optimal perioperative brain health

BP O'Gara, L Gao, ER Marcantonio… - …, 2021 - pmc.ncbi.nlm.nih.gov
Multicomponent interventions are effective in preventing postoperative delirium, and work is
ongoing to determine if they can be effective in preventing other postoperative …

Prevalence, risk factors, and impact of delirium on hospitalized older adults with dementia: a systematic review and meta-analysis

QYC Han, NG Rodrigues, P Klainin-Yobas… - Journal of the American …, 2022 - Elsevier
Objectives High prevalence of delirium superimposed on dementia (DSD) was previously
reported, with associated negative impact on hospitalized older adults. However, data were …

Epidemiology and risk factors for delirium across hospital settings

EE Vasilevskis, JH Han, CG Hughes, EW Ely - Best practice & research …, 2012 - Elsevier
Delirium is one of the most common causes of acute end-organ dysfunction across hospital
settings, occurring in as high as 80% of critically ill patients that require intensive care unit …

Risk factors for postoperative delirium following hip fracture repair in elderly patients: a systematic review and meta-analysis

Y Yang, X Zhao, T Dong, Z Yang, Q Zhang… - Aging clinical and …, 2017 - Springer
Background No formal systematic review or meta-analysis was performed up to now to
summarize the risk factors of delirium after hip surgery. Aims The present study aimed to …

Diagnostic accuracy of the CAM-ICU and ICDSC in detecting intensive care unit delirium: a bivariate meta-analysis

TJ Chen, YW Chung, HCR Chang, PY Chen… - International journal of …, 2021 - Elsevier
Background Delirium is a critical and highly prevalent problem among critically ill patients.
The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the Intensive …