Across the lifespan, the human body and brain endure the impact of a plethora of
exogenous and endogenous factors that determine the health outcome in old age. The …

Motion during the acquisition of magnetic resonance imaging (MRI) data degrades image
quality, hindering our capacity to characterise disease in patient populations. Quality control …

Cardiometabolic risk (CMR) factors are associated with accelerated brain aging and
increased risk for sex‐dimorphic illnesses such as Alzheimer's disease (AD). Yet, it is …

Importance Brain aging elicits complex neuroanatomical changes influenced by multiple
age-related pathologies. Understanding the heterogeneity of structural brain changes in …

Despite major advances, our understanding of the neurobiology of life course
socioeconomic conditions is still scarce. This study aimed to provide insight into the …

Given the unpredictable rapid onset and ubiquitous consequences of weight gain induced
by antipsychotics, there is a pressing need to get insights into the underlying processes at …

Our knowledge of the mechanisms underlying the vulnerability of the brain's white matter
microstructure to cardiovascular risk factors (CVRFs) is still limited. We used a quantitative …

Socioeconomic status (SES) plays a significant role in health and disease. At the same time,
early‐life conditions affect neural function and structure, suggesting the brain may be a …

Given controversial findings of reduced depressive symptom severity and increased
hippocampus volume in CYP2C19 poor metabolizers, we sought to provide empirical …

In face of cumulating evidence about the impact of human-induced environmental changes
on mental health and behavior, our understanding of the main effects and interactions …