Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …

In the past mitochondria were considered as the “powerhouse” of cell, since they generate
more than 90% of ATP in aerobic conditions through the oxidative phosphorylation …

Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid
peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular …

As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …

The mitochondria are essential organelles that generate large amounts of ATP via the
electron transport chain (ECT). Mitochondrial dysfunction causes reactive oxygen species …

Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy
regarding to their remarkable efficacy in controlling the inflammatory status in patients …

Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria
are essential organelles responsible for numerous physiologic processes, such as energy …

Nonalcoholic fatty liver disease (NAFLD) includes a broad spectrum of liver dysfunctions
and it is predicted to become the primary cause of liver failure and hepatocellular carcinoma …

The liver is an important metabolic and detoxification organ and hence demands a large
amount of energy, which is mainly produced by the mitochondria. Liver tissues of patients …

Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In
advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective …