Protein, as the material basis of vita, is the crucial undertaker of life activities, which
constitutes the framework and main substance of human tissues and organs, and takes part …

Downstream processing needs more innovative ideas to advance and overcome current
bioprocessing challenges. Chromatography is by far the most prevalent technique used by a …

The performance of the previously optimized magnetic cross-linked enzyme aggregate of
Eversa (Eversa-mCLEA) in the enzymatic synthesis of biolubricants by transesterification of …

Highlights•Process intensification enables more efficient biopharmaceutical downstream
processing.•Affinity precipitation allows the construction of a robust platform-compatible …

The demand for on-chip cancer cell separation in biomedical, bio-sensor, bio-detection,
personalized medicine, and clinical diagnostic fields has resulted in a variety of studies …

The demand for purified antibodies is ever-rising. This study presents a nanoparticle-based
material for efficient magnetic separation of immunoglobulin G (IgG) with high binding …

The use of benign stimuli to control the binding and release of labile biologics for their
isolation from complex feedstocks is a key goal of modern biopharmaceutical technology …

Proteins are essential for various functions such as brain activity and muscle contraction in
humans. Even though food is a source of proteins, the bioavailability of proteins in most …

A major difficulty to reach commercial-scale production for plant-made antibodies is the
complexity and cost of their purification from plant extracts. Here, using Protein A magnetic …

Current downstream processing of monoclonal antibodies (mAbs) is limited in throughput
and requires harsh pH conditions for mAb elution from Protein A affinity ligands. The use of …