Mesenchymal stromal cell-derived extracellular vesicles attenuate dendritic cell maturation and function
Mesenchymal stromal cells (MSCs) are potent regulators of immune responses largely
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are …
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are …
Cellular aging secretes: a comparison of bone-marrow-derived and induced mesenchymal stem cells and their secretome over long-term culture
A Marote, D Santos, B Mendes-Pinheiro… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) hold promising therapeutic potential in several clinical
applications, mainly due to their paracrine activity. The implementation of future secretome …
applications, mainly due to their paracrine activity. The implementation of future secretome …
Nature vs. nurture: defining the effects of mesenchymal stromal cell isolation and culture conditions on resiliency to palmitate challenge
As MSC products move from early development to clinical translation, culture conditions shift
from xeno-to xeno-free systems. However, the impact of isolation and culture-expansion …
from xeno-to xeno-free systems. However, the impact of isolation and culture-expansion …
Human platelet lysate can replace fetal calf serum as a protein source to promote expansion and osteogenic differentiation of human bone-marrow-derived …
M Karadjian, AS Senger, C Essers, S Wilkesmann… - Cells, 2020 - mdpi.com
Fetal calf serum (FCS) is frequently used as a growth factor and protein source in bone-
marrow-derived mesenchymal stromal cell (BMSC) culture media, although it is a xenogenic …
marrow-derived mesenchymal stromal cell (BMSC) culture media, although it is a xenogenic …
Pulsed Electric Fields for Valorization of Platelets with No Therapeutic Value towards a High Biomedical Potential Product—A Proof of Concept
D Salvador, H Almeida, D Rego, P Mendonça… - Applied Sciences, 2022 - mdpi.com
Featured Application Biomedical product development from PEF application into platelets.
Abstract Nowadays, the standard media used in clinical-scale mesenchymal stem cell …
Abstract Nowadays, the standard media used in clinical-scale mesenchymal stem cell …
Paving the road for mesenchymal stem cell-derived exosome therapy in bronchopulmonary dysplasia and pulmonary hypertension
Bronchopulmonary dysplasia (BPD) is a chronic neonatal lung disease characterized by
inflammation and arrest of alveolarization. Its common sequela, pulmonary hypertension …
inflammation and arrest of alveolarization. Its common sequela, pulmonary hypertension …
Human platelet lysate improves bone forming potential of human progenitor cells expanded in microcarrier-based dynamic culture
Xenogeneic-free media are required for translating advanced therapeutic medicinal
products to the clinics. In addition, process efficiency is crucial for ensuring cost efficiency …
products to the clinics. In addition, process efficiency is crucial for ensuring cost efficiency …
Manufacturing of human Wharton's jelly stem cells for clinical use: selection of serum is important
CM Kong, HD Lin, A Biswas, A Bongso, CY Fong - Cytotherapy, 2019 - Elsevier
Abstract Background Human Wharton's jelly–derived mesenchymal stromal cells (hWJSCs)
have gained considerable attention for their use in cell therapy. Many of these applications …
have gained considerable attention for their use in cell therapy. Many of these applications …
[HTML][HTML] Establishing a technique for isolation and characterization of human periodontal ligament derived mesenchymal stem cells
SR Banavar, SY Rawal, IC Paterson, G Singh… - The Saudi Dental …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are extensively used in tissue regenerative procedures.
One source of MSCs is the periodontal ligament (PDL) of teeth. Isolation of MSCs from …
One source of MSCs is the periodontal ligament (PDL) of teeth. Isolation of MSCs from …
[HTML][HTML] In vitro periodontal ligament cell expansion by co-culture method and formation of multi-layered periodontal ligament-derived cell sheets
IN Safi, BMA Hussein, AM Al-Shammari - Regenerative therapy, 2019 - Elsevier
Objective Per-implantitis is one of the implant treatment complications. Dentists have failed
to restore damaged periodontium by using conventional therapies. Tissue engineering …
to restore damaged periodontium by using conventional therapies. Tissue engineering …