Flourishing antibacterial strategies for osteomyelitis therapy

X Wang, M Zhang, T Zhu, Q Wei, G Liu… - Advanced …, 2023 - Wiley Online Library
Osteomyelitis is a destructive disease of bone tissue caused by infection with pathogenic
microorganisms. Because of the complex and long‐term abnormal conditions, osteomyelitis …

Design of photosensitizing agents for targeted antimicrobial photodynamic therapy

M Klausen, M Ucuncu, M Bradley - Molecules, 2020 - mdpi.com
Photodynamic inactivation of microorganisms has gained substantial attention due to its
unique mode of action, in which pathogens are unable to generate resistance, and due to …

Quaternary ammonium compounds: an antimicrobial mainstay and platform for innovation to address bacterial resistance

MC Jennings, KPC Minbiole… - ACS infectious diseases, 2015 - ACS Publications
Quaternary ammonium compounds (QACs) have represented one of the most visible and
effective classes of disinfectants for nearly a century. With simple preparation, wide structural …

Antimicrobial polymeric materials with quaternary ammonium and phosphonium salts

Y Xue, H Xiao, Y Zhang - International journal of molecular sciences, 2015 - mdpi.com
Polymeric materials containing quaternary ammonium and/or phosphonium salts have been
extensively studied and applied to a variety of antimicrobial-relevant areas. With various …

Pyridinium salts: from synthesis to reactivity and applications

S Sowmiah, JMSS Esperança, LPN Rebelo… - Organic Chemistry …, 2018 - pubs.rsc.org
Structurally diverse pyridinium salts are quite familiar structures in many natural products
and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played …

Structure–activity relationship of cationic surfactants as antimicrobial agents

C Zhou, Y Wang - Current Opinion in Colloid & Interface Science, 2020 - Elsevier
Cationic surfactants are widely used as antimicrobial agents in various fields. However, the
widespread use of cationic surfactants has caused huge accumulation in environment …

Chitosan-based hemostatic sponges as new generation hemostatic materials for uncontrolled bleeding emergency: Modification, composition, and applications

Z Liu, Y Xu, H Su, X Jing, D Wang, S Li, Y Chen… - Carbohydrate …, 2023 - Elsevier
The choice of hemostatic technique is a curial concern for surgery and as first-aid treatment
in combat. To treat uncontrolled bleeding in complex wound environments, chitosan-based …

Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Antimicrobial activity of quaternary ammonium salts: Structure-activity relationship

MN Nadagouda, P Vijayasarathy, A Sin, H Nam… - Medicinal Chemistry …, 2022 - Springer
Compounds with antimicrobial activity have gained much attention in research due to the
outbreak of coronavirus disease 2019 (COVID-19). Quaternary ammonium salts (QASs) are …

Discovery of Quaternized Pyridine-Thiazole-Pleuromutilin derivatives with broad-spectrum antibacterial and potent Anti-MRSA activity

J Xia, L Xin, J Li, L Tian, K Wu, S Zhang… - Journal of Medicinal …, 2023 - ACS Publications
The quaternization of compounds has emerged as a promising molecular design strategy for
the development of antibiotics. Herein, we report the design, synthesis, antibacterial …