The rough endoplasmic reticulum (ER) of nucleated human cells has crucial functions in
protein biogenesis, calcium (Ca2+) homeostasis, and signal transduction. Among the …

Gastric cancer (GC) has been recognized as the major reason for global cancer-associated
mortality. SEC62 homolog, preprotein translocation factor (SEC62) has been documented to …

The human SEC62 gene is located on chromosome 3q, was characterized as a tumor driver
gene and is found to be overexpressed in an ever-growing number of tumors, particularly …

Background and aims Sec62 is a membrane protein of the endoplasmic reticulum that
facilitates protein transport. Its role in cancer is increasingly recognised, but remains largely …

Simple Summary Amplification and overexpression of the SEC62 oncogene was reported in
a variety of human cancers and was associated with poor prognosis as well as lymph node …

The relation between atypical fibroxanthoma and pleomorphic dermal sarcoma has led to
confusion and debate in the literature. Both tumors present on sun-exposed skin, typically on …

Background Head and neck squamous cell carcinomas (HNSCC) are frequently diagnosed
in advanced stages, which limits therapeutic options and results in persistently poor patient …

The SEC62 gene encodes for a transmembrane protein of the endoplasmic reticulum (ER).
Sec62 protein is involved in the post‐translational transport of secretory and membrane …

A 79-year-old man presented with a 6-month history of four new painless enlarging scalp
lesions. He had a strong history of sun exposure but otherwise no previous skin cancers. On …

Objective: The present study aimed to analyze the mechanism by which long-term
occupational exposure of workers to low-dose ionizing irradiation induces epithelial …