Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

SL McGee, M Hargreaves - Nature Reviews Endocrinology, 2020 - nature.com
Exercise is fundamental for good health, whereas physical inactivity underpins many chronic
diseases of modern society. It is well appreciated that regular exercise improves metabolism …

[HTML][HTML] Exercise, GLUT4, and skeletal muscle glucose uptake

EA Richter, M Hargreaves - Physiological reviews, 2013 - journals.physiology.org
Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital
for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose …

Tracing the lactate shuttle to the mitochondrial reticulum

GA Brooks, CC Curl, RG Leija, AD Osmond… - … & molecular medicine, 2022 - nature.com
Isotope tracer infusion studies employing lactate, glucose, glycerol, and fatty acid isotope
tracers were central to the deduction and demonstration of the Lactate Shuttle at the whole …

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European …

L Rydén, E Standl, M Bartnik… - European heart …, 2007 - academic.oup.com
Task Forces, expert groups, or consensus panels. The chosen experts in these writing
panels are asked to provide disclosure statements of all relationships they may have, which …

The concept of maximal lactate steady state: a bridge between biochemistry, physiology and sport science

VL Billat, P Sirvent, G Py, JP Koralsztein, J Mercier - Sports medicine, 2003 - Springer
The maximal lactate steady state (MLSS) is defined as the highest blood lactate
concentration (MLSSc) and work load (MLSSw) that can be maintained over time without a …

Regulation of glucose and glycogen metabolism during and after exercise

TE Jensen, EA Richter - The Journal of physiology, 2012 - Wiley Online Library
Utilization of carbohydrate in the form of intramuscular glycogen stores and glucose
delivered from plasma becomes an increasingly important energy substrate to the working …

Glucose metabolism and catecholamines

E Barth, G Albuszies, K Baumgart… - Critical care …, 2007 - journals.lww.com
Until now, catecholamines were the drugs of choice to treat hypotension during shock states.
Catecholamines, however, also have marked metabolic effects, particularly on glucose …

A comparison of epinephrine and norepinephrine in critically ill patients

JA Myburgh, A Higgins, A Jovanovska, J Lipman… - Intensive care …, 2008 - Springer
Objective To determine whether there was a difference between epinephrine and
norepinephrine in achieving a mean arterial pressure (MAP) goal in intensive care (ICU) …

Exercise and regulation of carbohydrate metabolism

JD Mul, KI Stanford, MF Hirshman… - Progress in molecular …, 2015 - Elsevier
Carbohydrates are the preferred substrate for contracting skeletal muscles during high-
intensity exercise and are also readily utilized during moderate intensity exercise. This use …

Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review

GJ Kemp, M Meyerspeer… - NMR in Biomedicine: An …, 2007 - Wiley Online Library
Abstract 31P MRS offers a unique view of muscle metabolism in vivo, but correct
quantification is important. Inter‐study correlation of estimates of [Pi] and [phosphocreatine …