Ovarian cancer remains a challenging disease with limited treatment options and poor
prognosis. The tumor microenvironment (TME) plays a crucial role in tumor growth …

In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …

The tumor microenvironment is a highly complex and dynamic mixture of cell types,
including tumor, immune and endothelial cells (ECs), soluble factors (cytokines …

The tumor microenvironment (TME) is a highly intricate milieu, comprising a multitude of
components, including immune cells and stromal cells, that exert a profound influence on …

Ferroptosis is an iron-dependent regulatory form of cell death characterized by the
accumulation of intracellular reactive oxygen species and lipid peroxidation. It plays a critical …

This phase II trial aimed to determine the efficacy and safety of induction
chemoimmunotherapy of camrelizumab plus modified TPF in locally advanced …

Patients with human papillomavirus-negative head and neck squamous cell carcinoma
(HPV-negative HNSCC) have worse outcomes than HPV-positive HNSCC. In our study, we …

Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …

Background While T cell-activating immunotherapies against recurrent head and neck
squamous cell carcinoma (HNSCC) have shown impressive results in clinical trials, they are …

Malignancies represent a persisting worldwide health burden. Tumor treatment is commonly
based on surgical and/or non-surgical therapies. In the recent decade, novel non-surgical …