Genomic stability is critical for the clinical use of human embryonic and induced pluripotent
stem cells. We performed high-resolution SNP (single-nucleotide polymorphism) analysis on …

High‐grade osteosarcoma is an extremely genomically unstable tumor. This, together with
other challenges, such as the heterogeneity within and between tumor samples, and the …

Over the last three decades, cytogenetic analysis of malignancies has become an integral
part of disease evaluation and prediction of prognosis or responsiveness to therapy. In most …

High‐grade osteosarcoma is a tumor with a complex genomic profile, occurring primarily in
adolescents with a second peak at middle age. The extensive genomic alterations obscure …

Background Osteosarcomas are the most common non-haematological primary malignant
tumours of bone, and all conventional osteosarcomas are high-grade tumours showing …

Background Osteosarcomas are the most common primary malignant tumors of bone,
showing complex chromosomal rearrangements with multiple gains and losses. A frequent …

Multiple myeloma can be divided into two distinct genetic subgroups: hyperdiploid (HRD) or
nonhyperdiploid (NHRD) myeloma. Myeloma cell lines are important tools to study myeloma …

Despite recent advances in osteosarcoma diagnosis and therapy, much remains unclear
about the molecular mechanisms involved in the disorder, and the discovery of novel drug …

Background High-throughput profiling of human tissues typically yield as results the gene
lists comprised of a mix of relevant molecular entities with multiple false positives that …

High-throughput profiling of human tissues typically yields the gene lists composed of a
variety of more or less relevant molecular entities. These lists are riddle by false positive …