[HTML][HTML] Human adult neurogenesis: evidence and remaining questions

G Kempermann, FH Gage, L Aigner, H Song, MA Curtis… - Cell stem cell, 2018 - cell.com
Renewed discussion about whether or not adult neurogenesis exists in the human
hippocampus, and the nature and strength of the supporting evidence, has been reignited …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Quiescence of adult mammalian neural stem cells: a highly regulated rest

N Urbán, IM Blomfield, F Guillemot - Neuron, 2019 - cell.com
Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

Neurogenesis in the adult hippocampus

G Kempermann, H Song… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Chronic stress and glucocorticoids: from neuronal plasticity to neurodegeneration

S Vyas, AJ Rodrigues, JM Silva, F Tronche… - Neural …, 2016 - Wiley Online Library
Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …

Microglia and the brain: complementary partners in development and disease

TR Hammond, D Robinton… - Annual review of cell and …, 2018 - annualreviews.org
An explosion of findings driven by powerful new technologies has expanded our
understanding of microglia, the resident immune cells of the central nervous system (CNS) …

Adult neurogenesis in mammals

FH Gage - Science, 2019 - science.org
The first claim, in the early 1960s, that neurons could be generated in the postnatal
mammalian brain was met with considerable skepticism and controversy (1). Over the next …

Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained

MS Nokia, S Lensu, JP Ahtiainen… - The Journal of …, 2016 - Wiley Online Library
Key points Aerobic exercise, such as running, enhances adult hippocampal neurogenesis
(AHN) in rodents. Little is known about the effects of high‐intensity interval training (HIT) or …

Functional neurochemistry of the ventral and dorsal hippocampus: stress, depression, dementia and remote hippocampal damage

NV Gulyaeva - Neurochemical Research, 2019 - Springer
The hippocampus is not a homogeneous brain area, and the complex organization of this
structure underlies its relevance and functional pleiotropism. The new data related to the …

Born this way: Hippocampal neurogenesis across the lifespan

DA Kozareva, JF Cryan, YM Nolan - Aging cell, 2019 - Wiley Online Library
The capability of the mammalian brain to generate new neurons through the lifespan has
gained much attention for the promise of new therapeutic possibilities especially for the …