Variability of physiological brain perfusion in healthy subjects–A systematic review of modifiers. Considerations for multi-center ASL studies
Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …
Standardization of measurement conditions and correction for important modifiers is …
Distribution of cardiac output to the brain across the adult lifespan
A widely accepted dogma is that about 15–20% of cardiac output is received by the brain in
healthy adults under resting conditions. However, it is unclear if the distribution of cardiac …
healthy adults under resting conditions. However, it is unclear if the distribution of cardiac …
Effects of 5 years aerobic exercise on cognition in older adults: the generation 100 study: a randomized controlled trial
Objective The objective of this study was to investigate whether a 5-year exercise
intervention and change in peak oxygen uptake (VO _ 2 peak VO 2 peak) is associated with …
intervention and change in peak oxygen uptake (VO _ 2 peak VO 2 peak) is associated with …
Higher VO2max is associated with thicker cortex and lower grey matter blood flow in older adults
VO2max (maximal oxygen consumption), a validated measure of aerobic fitness, has been
associated with better cerebral artery compliance and measures of brain morphology, such …
associated with better cerebral artery compliance and measures of brain morphology, such …
[HTML][HTML] Determinants of cerebral blood flow and arterial transit time in healthy older adults
Cerebral blood flow (CBF) and arterial transit time (ATT), markers of brain vascular health,
worsen with age. The primary aim of this cross-sectional study was to identify modifiable …
worsen with age. The primary aim of this cross-sectional study was to identify modifiable …
Cardiorespiratory fitness diminishes the effects of age on white matter hyperintensity volume
NF Johnson, AA Bahrani, DK Powell, GA Jicha… - PLoS …, 2020 - journals.plos.org
White matter hyperintensities (WMHs) are among the most commonly observed marker of
cerebrovascular disease. Age is a key risk factor for WMH development. Cardiorespiratory …
cerebrovascular disease. Age is a key risk factor for WMH development. Cardiorespiratory …
Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort
CJ Vesperman, V Pozorski, RJ Dougherty… - Alzheimer's Research & …, 2018 - Springer
Background Age is the cardinal risk factor for Alzheimer's disease (AD), and white matter
hyperintensities (WMH), which are more prevalent with increasing age, may contribute to …
hyperintensities (WMH), which are more prevalent with increasing age, may contribute to …
Implications of habitual endurance and resistance exercise for dynamic cerebral autoregulation
New Findings What is the central question of this study? Does habitual resistance and
endurance exercise modify dynamic cerebral autoregulation? What is the main finding and …
endurance exercise modify dynamic cerebral autoregulation? What is the main finding and …
Literature Review on the Effectiveness and Required Dosages of Cognitive Interventions for Older Adults
RG Winningham, AJ Pacheco - Topics in Geriatric Rehabilitation, 2024 - journals.lww.com
Objective: The purpose of this article is to review interventions that have been shown to
improve cognitive abilities in older adults, including aerobic training, resistance training …
improve cognitive abilities in older adults, including aerobic training, resistance training …
Cardiorespiratory fitness and cognition in persons at risk for Alzheimer's disease
CJ Vesperman, R Wang, SA Schultz… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction This study examined the relationship between cardiorespiratory fitness (CRF)
and longitudinal cognitive functioning in a cohort enriched with risk factors for Alzheimer's …
and longitudinal cognitive functioning in a cohort enriched with risk factors for Alzheimer's …