Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …

The structural integrity and functional stability of organelles are prerequisites for the viability
and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the …

The current coronavirus disease 2019 (COVID-19) pandemic presents a global public health
challenge. The viral pathogen responsible, severe acute respiratory syndrome coronavirus 2 …

The roles and regulatory mechanisms of ferroptosis (a non-apoptotic form of cell death) in
cancer remain unclear. The tumour suppressor BRCA1-associated protein 1 (BAP1) …

Effective maintenance and stability of our genomes is essential for normal cell division,
tissue homeostasis, and cellular and organismal fitness. The processes of chromosome …

The removal of damaged or superfluous organelles from the cytosol by selective autophagy
is required to maintain organelle function, quality control and overall cellular homeostasis …

The Wnt/β‐catenin signalling pathway is pivotal for stem cell function and the control of
cellular differentiation, both during embryonic development and tissue homeostasis in …

The LKB1/AMPK pathway plays a major role in cellular homeostasis and tumor suppression.
Down-regulation of LKB1/AMPK occurs in several human cancers and has been implicated …

ADP-ribosylation (ADPr) is a reversible post-translational modification of proteins, which
controls major cellular and biological processes, including DNA damage repair, cell …

Abstract Poly (ADP-ribose) Polymerase 1 (PARP1), one of the most investigated 18
membered PARP family enzymes, is involved in a variety of cellular functions including DNA …