Imaging extracellular vesicles: current and emerging methods

STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …

[HTML][HTML] Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine

A González-González, D García-Sánchez… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer

H Nie, X Xie, D Zhang, Y Zhou, B Li, F Li, F Li, Y Cheng… - Nanoscale, 2020 - pubs.rsc.org
Engineered exosomes have become popular drug delivery carriers for cancer treatment.
This is partially due to the interesting property, ie exosome organotropism, which plays an …

Isolation and analysis methods of extracellular vesicles (EVs)

Z Zhao, H Wijerathne, AK Godwin… - … vesicles and circulating …, 2020 - pmc.ncbi.nlm.nih.gov
Extracellular vesicles (EVs) have been recognized as an evolving biomarker within the
liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs …

Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1

H Wu, X Mu, L Liu, H Wu, X Hu, L Chen, J Liu… - Cell Death & …, 2020 - nature.com
Exosomes are small endogenous membrane vesicles that can mediate cell communication
by transferring genetic materials. Based on that, exosomes have always been discussed as …

Exosomes regulate the transformation of cancer cells in cancer stem cell homeostasis

J Xu, K Liao, W Zhou - Stem cells international, 2018 - Wiley Online Library
In different biological model systems, exosomes are considered mediators of cell‐cell
communication between different cell populations. Exosomes, as extracellular vesicles …

Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes

U Altanerova, J Jakubechova… - … journal of cancer, 2019 - Wiley Online Library
The natural behavior of mesenchymal stem cells (MSCs) and their exosomes in targeting
tumors is a promising approach for curative therapy. Human tumor tropic mesenchymal stem …

Exosomal MicroRNAs and organotropism in breast cancer metastasis

GL Wong, S Abu Jalboush, HW Lo - Cancers, 2020 - mdpi.com
Breast cancer is the most frequent malignancy for women in which one in eight women will
be diagnosed with the disease in their lifetime. Despite advances made in treating primary …

Update review on five top clinical applications of human amniotic membrane in regenerative medicine

AR Nejad, AA Hamidieh, MA Amirkhani, MM Sisakht - Placenta, 2021 - Elsevier
Due to the increasing number of studies performed in the field of regenerative medicine
during the last two decades, more analytic studies are still needed to clarify the future …

Extracellular vesicles from human liver stem cells inhibit renal cancer stem cell‐derived tumor growth in vitro and in vivo

A Brossa, V Fonsato, C Grange, S Tritta… - … Journal of Cancer, 2020 - Wiley Online Library
Cancer stem cells (CSCs) are considered as responsible for initiation, maintenance and
recurrence of solid tumors, thus representing the key for tumor eradication. The antitumor …