Role of seipin in human diseases and experimental animal models

Y Li, X Yang, L Peng, Q Xia, Y Zhang, W Huang, T Liu… - Biomolecules, 2022 - mdpi.com
Seipin, a protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2)
gene, is famous for its key role in the biogenesis of lipid droplets and type 2 congenital …

[HTML][HTML] Diet-Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss

C McGrath, SE Little-Letsinger, GM Pagnotti, B Sen… - Obesity Facts, 2024 - karger.com
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work
showed both no effect and a decrement in bone density or quality when obesity begins prior …

The skeleton in a physical world

J Rubin, M Styner - Experimental Biology and Medicine, 2022 - journals.sagepub.com
All organisms exist within a physical space and respond to physical forces as part of daily
life. In higher organisms, the skeleton is critical for locomotion in the physical environment …

Effects of seipin on mouse mesenchymal stem cell Osteo-Adipogenic Balance

Z Li, S Jin, T Xu, H Chen, W Cai, J Du, J Qiu… - Stem Cells and …, 2024 - liebertpub.com
Seipin deficiency is an important cause of type 2 Berardinelli-Seip congenital dyslipidemia
(BSCL2). BSCL2 is a severe lipodystrophy syndrome with lack of adipose tissue, hepatic …

[PDF][PDF] Diet-Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss

CMGSE Little-Letsingera, GMPB Sena, MA Stynerd… - 2024 - scienceopen.com
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work
showed both no effect and a decrement in bone density or quality when obesity begins prior …