Factors affecting the synthesis of bovine serum albumin nanoparticles using the desolvation method

YP Tanjung, MK Dewi, VA Gatera… - Nanotechnology …, 2024 - Taylor & Francis
Currently, protein-based nanoparticles are in high demand as drug delivery systems due to
their exceptional qualities, including nontoxicity, nonantigenicity, and biodegradability. Other …

[HTML][HTML] Nano pharmaceutical delivery in combating colorectal cancer

SK Singh, R Solanki, S Patel - Medicine in Drug Discovery, 2024 - Elsevier
Colorectal cancer (CRC), ranking as the third most common cancer globally, is associated
with a high death rate. The colon, also known as the large intestine, is the site where …

Synthesis, characterization, in-silico and in-vitro anticancer studies of Plumbagin encapsulated albumin nanoparticles for breast cancer treatment

R Solanki, M Saini, J Mochi, A Pappachan… - Journal of Drug Delivery …, 2023 - Elsevier
Abstract Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is a naturally occurring
phytochemical, mainly found in the roots of the Plumbago zeylanica L. Plumbagin (PLB) …

A theoretical approach on the possibility of using α-phographene, g-X3N4 nanosheets, and C19X fullerenes for adsorption and drug delivery of a proteasome inhibitor …

SA Siadati, MA Ebrahimzadeh… - Diamond and Related …, 2024 - Elsevier
Bortezomib is a key agent for treatment of cancer; while, it is a very hazardous bioactive
substance (for healthy tissues). Therefore, delivering this drug to the targeted cancerous …

Preparation, characterization and in vitro anticancer efficacy of biotin-conjugated, silibinin loaded bovine serum albumin nanoparticles

R Solanki, S Patel - Food Bioscience, 2023 - Elsevier
Silibinin (SBN) is a natural, plant-derived bioactive flavonolignan, possessing wide range of
pharmaceutical activities including anticancer. However, poor aqueous solubility and low …

Folate functionalized and evodiamine‐loaded pluronic nanomicelles for augmented cervical cancer cell killing

R Solanki, AK Jangid, M Jadav… - Macromolecular …, 2023 - Wiley Online Library
Evodiamine (Evo) is a natural, biologically active plant alkaloid with wide range of
pharmacological activities. In the present study Evo‐loaded folate‐conjugated Pluronic F108 …

Folate conjugated albumin as a targeted nanocarrier for the delivery of fisetin: in silico and in vitro biological studies

R Solanki, AK Srivastav, S Patel, SK Singh, B Jodha… - RSC …, 2024 - pubs.rsc.org
Fisetin (FST), a natural flavonoid compound derived from various fruits and vegetables,
including apple, strawberry, and onion, demonstrates potential for a wide range of …

Formulation development, characterization and anti-cancer study of a nanocarrier based on albumin nanoparticles and exosome for carboplatin sustained release

M Saeidifar, AA Saboury, R Macgregor - Journal of Molecular Liquids, 2024 - Elsevier
Efficient delivery of antitumor drugs is an important area in the scientific community because
of their effective distribution, high bioavailability, and improved therapeutic value. Herein, a …

Protein nanocarriers for the delivery of phytoconstituents

R Solanki, S Patel - Nanotechnology Based Delivery of Phytoconstituents …, 2024 - Springer
Phytoconstituents are well known for their anticancer activities. They are considered as the
best alternatives of chemotherapeutic drugs because of their less toxicity to healthy cells and …

Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

CB Braga, JC Milan, MA Meirelles, B Zavan… - RSC Medicinal …, 2024 - pubs.rsc.org
Conjugation of the naturally occurring product piplartine (PPT, 1), which is a potent cytotoxic
compound and ROS inducer, with a diphenyl sulfonyl-substituted furoxan moiety (namely, 3 …