Colorectal cancer (CRC), ranking as the third most common cancer globally, is associated with a high death rate. The colon, also known as the large intestine, is the site where …
Abstract Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is a naturally occurring phytochemical, mainly found in the roots of the Plumbago zeylanica L. Plumbagin (PLB) …
Bortezomib is a key agent for treatment of cancer; while, it is a very hazardous bioactive substance (for healthy tissues). Therefore, delivering this drug to the targeted cancerous …
Silibinin (SBN) is a natural, plant-derived bioactive flavonolignan, possessing wide range of pharmaceutical activities including anticancer. However, poor aqueous solubility and low …
R Solanki, AK Jangid, M Jadav… - Macromolecular …, 2023 - Wiley Online Library
Evodiamine (Evo) is a natural, biologically active plant alkaloid with wide range of pharmacological activities. In the present study Evo‐loaded folate‐conjugated Pluronic F108 …
Fisetin (FST), a natural flavonoid compound derived from various fruits and vegetables, including apple, strawberry, and onion, demonstrates potential for a wide range of …
M Saeidifar, AA Saboury, R Macgregor - Journal of Molecular Liquids, 2024 - Elsevier
Efficient delivery of antitumor drugs is an important area in the scientific community because of their effective distribution, high bioavailability, and improved therapeutic value. Herein, a …
R Solanki, S Patel - Nanotechnology Based Delivery of Phytoconstituents …, 2024 - Springer
Phytoconstituents are well known for their anticancer activities. They are considered as the best alternatives of chemotherapeutic drugs because of their less toxicity to healthy cells and …
CB Braga, JC Milan, MA Meirelles, B Zavan… - RSC Medicinal …, 2024 - pubs.rsc.org
Conjugation of the naturally occurring product piplartine (PPT, 1), which is a potent cytotoxic compound and ROS inducer, with a diphenyl sulfonyl-substituted furoxan moiety (namely, 3 …