In 1841, the extraction of hematoporphyrin from dried blood by removing iron marked the
birth of the photosensitizer. The last twenty years has witnessed extensive research in the …

The cationic porphyrin meso-tetra (4-N-methylpyridyl) porphine (TMPyP) has a high yield of
singlet oxygen generation upon light activation and a strong affinity for DNA. These …

Tumors located in the oral mucosa are challenging to treat since surgery can lead to
aesthetic, speech, and salivation problems, radiotherapy alone is often ineffective, and …

A substantial drug release from poly (lactic-co-glycolic) acid (PLGA) micro-and nanoparticles
can occur in the first hours of immersion, which is referred to as burst release. A strong burst …

Topical ophthalmic antibiotics show low efficacy due to the well-known physiological
defense mechanisms of the eye, which prevents the penetration of exogenous substances …

In general, nanometer-sized drug delivery systems have a natural tendency for
accommodation in the follicular cavities, which makes them advantageous in the treatment …

Topical drug delivery is an interesting approach to treat skin diseases and to avoid pain and
low patient compliance in cases where a systemic delivery is required. However, the stratum …

Iontophoresis is a physical drug delivery enhancing technique that was introduced at the
beginning of the preceding century. For decades, iontophoresis research was focused on …

Given the hypothesis that microparticles can penetrate the skin barrier along the
transfollicular route, this work aimed to obtain and characterise chitosan microparticles …

Introduction Iontophoresis therapy (IPT) is a noninvasive technique that uses electrical
impulses to deliver charged molecules into the skin for controlled and targeted drug delivery …