The bipolar prodrome: meta-analysis of symptom prevalence prior to initial or recurrent mood episodes

AR Van Meter, C Burke, EA Youngstrom… - Journal of the American …, 2016 - Elsevier
Objective The aim of this study was to meta-analyze the prevalence of symptoms before an
initial mood episode of bipolar disorder (BD) and the prevalence of subthreshold symptoms …

Pre-pubertal bipolar disorder: origins and current status of the controversy

A Duffy, G Carlson, B Dubicka… - International Journal of …, 2020 - Springer
Background Evidence from epidemiological, clinical and high-risk studies has established
that the peak period of risk for onset of bipolar disorder spans late adolescence and early …

Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies

D Rasic, T Hajek, M Alda, R Uher - Schizophrenia bulletin, 2014 - academic.oup.com
Objective: Offspring of parents with severe mental illness (SMI; schizophrenia, bipolar
disorder, major depressive disorder) are at an increased risk of developing mental illness …

The developmental trajectory of bipolar disorder

A Duffy, J Horrocks, S Doucette… - The British Journal of …, 2014 - cambridge.org
BackgroundBipolar disorder is highly heritable and therefore longitudinal observation of
children of affected parents is important to mapping the early natural history. AimsTo model …

The emergent course of bipolar disorder: observations over two decades from the Canadian high-risk offspring cohort

A Duffy, S Goodday… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: The authors sought to describe the emergent course of bipolar disorder in
offspring of affected parents subgrouped by parental response to lithium prophylaxis …

Using structural MRI to identify bipolar disorders–13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group

A Nunes, HG Schnack, CRK Ching, I Agartz… - Molecular …, 2020 - nature.com
Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective
biological markers, such as those based on brain imaging, could aid in clinical management …

The Dutch bipolar offspring study: 12-year follow-up

E Mesman, WA Nolen, CG Reichart… - American Journal of …, 2013 - Am Psychiatric Assoc
Objective Offspring of bipolar parents have a genetically increased risk of developing mood
disorders. In a longitudinal study, the authors followed a bipolar offspring cohort from …

[图书][B] The Intelligent Clinician's Guide to the DSM-5?

J Paris - 2015 - books.google.com
The Intelligent Clinician's Guide to the DSM-5? is the second edition of the widely-read book
first published in 2013. This second edition is thoroughly revised, and has several new …

Brain age in early stages of bipolar disorders or schizophrenia

T Hajek, K Franke, M Kolenic, J Capkova… - Schizophrenia …, 2019 - academic.oup.com
Background The greater presence of neurodevelopmental antecedants may differentiate
schizophrenia from bipolar disorders (BD). Machine learning/pattern recognition allows us to …

A high-risk study of bipolar disorder: childhood clinical phenotypes as precursors of major mood disorders

JI Nurnberger, M McInnis, W Reich… - Archives of general …, 2011 - jamanetwork.com
Context The childhood precursors of adult bipolar disorder (BP) are still a matter of
controversy. Objective To report the lifetime prevalence and early clinical predictors of …