An overview of clinical and commercial impact of drug delivery systems

AC Anselmo, S Mitragotri - Journal of Controlled Release, 2014 - Elsevier
Drug delivery systems are widely researched and developed to improve the delivery of
pharmaceutical compounds and molecules. The last few decades have seen a marked …

Approaches for enhancing oral bioavailability of peptides and proteins

J Renukuntla, AD Vadlapudi, A Patel… - International journal of …, 2013 - Elsevier
Oral delivery of peptide and protein drugs faces immense challenge partially due to the
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …

Hydrogels in biology and medicine: from molecular principles to bionanotechnology

NA Peppas, JZ Hilt, A Khademhosseini… - Advanced …, 2006 - Wiley Online Library
Hydrophilic polymers are the center of research emphasis in nanotechnology because of
their perceived “intelligence”. They can be used as thin films, scaffolds, or nanoparticles in a …

Designing materials for biology and medicine

R Langer, DA Tirrell - Nature, 2004 - nature.com
Biomaterials have played an enormous role in the success of medical devices and drug
delivery systems. We discuss here new challenges and directions in biomaterials research …

Stimuli-reponsive polymers and their bioconjugates

ES Gil, SM Hudson - Progress in polymer science, 2004 - Elsevier
Stimuli responsive polymers can provide a variety of applications for the biomedical fields.
The interest in these polymers has exponentially increased due to their promising potential …

Biomaterials: where we have been and where we are going

BD Ratner, SJ Bryant - Annu. Rev. Biomed. Eng., 2004 - annualreviews.org
▪ Abstract Since its inception just over a half century ago, the field of biomaterials has seen a
consistent growth with a steady introduction of new ideas and productive branches. This …

Advances in biomaterials, drug delivery, and bionanotechnology

R Langer, NA Peppas - AIChE Journal, 2003 - Wiley Online Library
Biomaterials are widely used in numerous medical applications. Chemical engineering has
played a central role in this research and development. Polymers as biomaterials, materials …

[图书][B] Handbook of encapsulation and controlled release

M Mishra - 2015 - books.google.com
Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

Challenges for the oral delivery of macromolecules

M Goldberg, I Gomez-Orellana - Nature reviews Drug discovery, 2003 - nature.com
The rapid integration of new technologies by the pharmaceutical industry has resulted in
numerous breakthroughs in the discovery, development and manufacturing of …

Drug transport mechanisms and release kinetics from molecularly designed poly (acrylic acid-g-ethylene glycol) hydrogels

L Serra, J Doménech, NA Peppas - Biomaterials, 2006 - Elsevier
Controlled drug release devices of pH-sensitive, complexing poly (acrylic acid-g-ethylene
glycol)(P (AA-g-EG)) hydrogels were prepared by free radical solution UV polymerization …