Although anxiety disorders represent a major societal problem demanding new therapeutic targets, these efforts have languished in the absence of a mechanistic understanding of this …
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and animal behavioral genetics that is designed to introduce students in the behavioral …
S Brummelte, E Mc Glanaghy, A Bonnin, TF Oberlander - Neuroscience, 2017 - Elsevier
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development, regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
A fundamental function of the brain is to evaluate the emotional and motivational significance of stimuli and to adapt behaviour accordingly. The IMAGEN study is the first …
Adolescence is a period of major risk for depression, which is associated with negative personal, social, and educational outcomes. Yet, in comparison to adult models of …
SZ Sabol, S Hu, D Hamer - Human genetics, 1998 - Springer
We describe a new polymorphism upstream of the gene for monoamine oxidase A (MAOA), an important enzyme in human physiology and behavior. The polymorphism, which is …
S Garbarino, P Lanteri, P Durando… - International journal of …, 2016 - mdpi.com
Sleep disorders are frequent (18%–23%) and constitute a major risk factor for psychiatric, cardiovascular, metabolic or hormonal co-morbidity and mortality. Low social status or …
MS Ansorge, M Zhou, A Lira, R Hen, JA Gingrich - Science, 2004 - science.org
Reduced serotonin transporter (5-HTT) expression is associated with abnormal affective and anxiety-like symptoms in humans and rodents, but the mechanism of this effect is unknown …
Evidence from diverse literatures supports the viewpoint that two modes of self-regulation exist, a lower-order system that responds quickly to associative cues of the moment and a …