MicroRNAs in breast cancer: Roles, functions, and mechanism of actions

M Abolghasemi, SS Tehrani, T Yousefi… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer is one of the most lethal malignancies in women in the world. Various factors
are involved in the development and promotion of the malignancy; most of them involve …

[HTML][HTML] Therapeutic delivery of tumor suppressor miRNAs for breast cancer treatment

SS Shinde, S Ahmed, JA Malik, U Hani, A Khanam… - Biology, 2023 - mdpi.com
Simple Summary The most frequent cancer in women is breast cancer (BC), which presents
a significant risk to their good health. Over the past few decades, several factors have …

[HTML][HTML] Covalent strategies for targeting messenger and non-coding RNAs: an updated review on siRNA, miRNA and antimiR conjugates

S Grijalvo, A Alagia, AF Jorge, R Eritja - Genes, 2018 - mdpi.com
Oligonucleotide-based therapy has become an alternative to classical approaches in the
search of novel therapeutics involving gene-related diseases. Several mechanisms have …

The role of microRNAs regulating the expression of matrix metalloproteinases (MMPs) in breast cancer development, progression, and metastasis

M Javadian, T Gharibi, N Shekari… - Journal of Cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) regulate several biological and physiological processes in
mammalian cells, including cellular proliferation, differentiation, apoptosis, and metabolism …

[HTML][HTML] Targeting PDK4 inhibits breast cancer metabolism

MR Guda, S Asuthkar, CM Labak… - American journal of …, 2018 - ncbi.nlm.nih.gov
Dysregulated metabolism in the form of aerobic glycolysis occurs in many cancers including
breast carcinoma. Here, we report PDK4 (pyruvate dehydrogenase kinase 4) as key enzyme …

Differential role of microRNAs in the pathogenesis and treatment of Esophageal cancer

M Hemmatzadeh, H Mohammadi, M Karimi… - Biomedicine & …, 2016 - Elsevier
Esophageal cancer (EC) is the most invasive disease associated with inclusive poor
prognosis. EC usually is found as either adenocarcinoma (EAC) or squamous cell …

[HTML][HTML] miR‑140‑3p inhibits breast cancer proliferation and migration by directly regulating the expression of tripartite motif 28

Y Zhou, B Wang, Y Wang, G Chen… - Oncology …, 2019 - spandidos-publications.com
The present study aimed to determine the expression profile and significance of microRNA‑
140‑3p (miR‑140‑3p) in breast cancer (BC). miR‑140‑3p expression in BC tumor tissues and …

[HTML][HTML] LncRNA SNHG12 ameliorates brain microvascular endothelial cell injury by targeting miR-199a

FQ Long, QJ Su, JX Zhou, DS Wang, PX Li… - Neural regeneration …, 2018 - journals.lww.com
Long non-coding RNAs regulate brain microvascular endothelial cell death, the
inflammatory response and angiogenesis during and after ischemia/reperfusion and oxygen …

HuR promotes breast cancer cell proliferation and survival via binding to CDK3 mRNA

Z Zhang, A Huang, A Zhang, C Zhou - Biomedicine & Pharmacotherapy, 2017 - Elsevier
HuR, a ubiquitously expressed RNA-binding protein, stabilizes mRNA and regulates its
translation. HuR expression was increased at all stages of breast cancer and correlated with …

MicroRNA-421 inhibits breast cancer metastasis by targeting metastasis associated 1

Y Pan, G Jiao, C Wang, J Yang, W Yang - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Dysregulation of microRNAs is involved in the initiation and progression of several human
cancers, including breast cancer, as strong evidence of miRNAs acting as oncogenes or …